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Study · Animal study (in vivo) · rat · 2005

3 results

Transmucosal macromolecular drug delivery.

Prego C, García M, Torres D, Alonso MJ

Journal of controlled release : official journal of the Controlled Release Society1 Jan 2005Cited by 194 (Europe PMC)

PMID15588901 (opens in a new tab)DOI10.1016/j.jconrel.2004.07.030 (opens in a new tab)PepBankPUB-15588901
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Activity measurement

    In rats, salmon calcitonin-loaded chitosan-coated nanocapsules and nanoparticles produced a marked, long-lasting decrease in calcemia.

    In plain wordsIn rats, salmon calcitonin-loaded chitosan-coated nanocapsules and nanoparticles markedly reduced blood calcium for a prolonged period.

    Peptide
    Calcitonin-salmon
    Outcome
    DecreaseCalcemia
    Study

    ratn: not reported in source

    rats
    Outcome group
    Bone and joint · Musculoskeletal
    Studied dose
    Dose not stated · intestinalAs given in this study (rat).

    Source sentences

    Summary
    Indeed, both CS-coated systems (nanocapsules and CS-coated nanoparticles) showed an important capacity to enhance the intestinal absorption of the model peptide, salmon calcitonin, as shown by the important and long-lasting decrease in the calcemia levels observed in rats.

Studies that did not test the peptide alone2

In this study, Calcitonin-salmon was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Calcitonin-salmon.

  1. 02AnimalNot a test of Calcitonin-salmon aloneAnimal study (in vivo)Pharmacokinetics

    In rats, chitosan-coated nanocapsules enhanced intestinal absorption of salmon calcitonin.

    In plain wordsIn rats, chitosan-coated nanocapsules increased intestinal absorption of salmon calcitonin.

    Peptide
    Calcitonin-salmon
    Outcome
    IncreaseIntestinal absorption with nanocapsules
    Study

    ratn: not reported in source

    rats
    Outcome group
    Pharmacokinetics · Pharmacology

    Source sentences

    Summary
    Indeed, both CS-coated systems (nanocapsules and CS-coated nanoparticles) showed an important capacity to enhance the intestinal absorption of the model peptide, salmon calcitonin, as shown by the important and long-lasting decrease in the calcemia levels observed in rats.

    In this study, Calcitonin-salmon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Calcitonin-salmon.

  2. 03AnimalNot a test of Calcitonin-salmon aloneAnimal study (in vivo)Pharmacokinetics

    In rats, chitosan-coated nanoparticles enhanced intestinal absorption of salmon calcitonin.

    In plain wordsIn rats, chitosan-coated nanoparticles increased intestinal absorption of salmon calcitonin.

    Peptide
    Calcitonin-salmon
    Outcome
    IncreaseIntestinal absorption with nanoparticles
    Study

    ratn: not reported in source

    rats
    Outcome group
    Pharmacokinetics · Pharmacology

    Source sentences

    Summary
    Indeed, both CS-coated systems (nanocapsules and CS-coated nanoparticles) showed an important capacity to enhance the intestinal absorption of the model peptide, salmon calcitonin, as shown by the important and long-lasting decrease in the calcemia levels observed in rats.

    In this study, Calcitonin-salmon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Calcitonin-salmon.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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