In women undergoing ovarian stimulation, cetrorelix alone produced significantly lower oestradiol per follicle than the other groups (leuprolide acetate, and cetrorelix with r-hLH).
In plain wordsIn women undergoing ovarian stimulation, cetrorelix alone gave lower oestradiol per follicle than the other groups, which were leuprolide acetate and cetrorelix with r-hLH.
- Peptide
- Cetrorelix
- Outcome
- DecreaseOestradiol per follicle
- Study
n = 74
- Comparator
- The other groups: leuprolide acetate, and cetrorelix with r-hLH
- Outcome group
- Sex hormones and fertility · Reproductive and sexual health
- Studied dose
- 3 mgAs given in this study (human).
Source sentences
The group treated with cetrorelix alone had a significantly lower concentration of oestradiol per follicle compared with the other groups.
2 context sentences(design, population, supporting numbers)
An open label, randomized, multi-centre study was performed to compare cetrorelix and leuprolide acetate for prevention of premature LH surge and to assess whether patients treated with cetrorelix benefit from addition of recombinant human (r-h)LH.
Normo-ovulatory women (n = 74) undergoing ovarian stimulation prior to intracytoplasmic sperm injection were treated with leuprolide acetate (n = 25) before ovarian stimulation with recombinant human FSH (r-hFSH) or with cetrorelix 3 mg on stimulation day 7 (with (n = 25) or without (n = 24) r-hLH 150 IU on days 7-10).