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Study · Animal study (in vivo) · prairie vole · 2005

2 results

Neonatal manipulation of oxytocin influences female reproductive behavior and success.

Cushing BS, Levine K, Cushing NL

Hormones and behavior1 Jan 2005Cited by 22 (Europe PMC)

PMID15579262 (opens in a new tab)DOI10.1016/j.yhbeh.2004.08.004 (opens in a new tab)PepBankPUB-15579262
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In female prairie voles, a neonatal oxytocin injection did not change the probability of mating at about 75 days of age.

    In plain wordsIn female prairie voles, oxytocin injected after birth did not change how likely they were to mate later in life.

    Peptide
    Oxytocin
    Outcome
    No significant changeProbability of mating in adult females
    Study

    prairie volen: not reported in source

    Comparator
    Saline and handled controls
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · intraperitonealAs given in this study (prairie vole).

    Source sentences

    Summary
    Treatment had no effect on the probability of mating.
    2 context sentences
    Summary · context
    To test this hypothesis, female prairie voles (Microtus ochrogaster) received one of four treatments within 24 h of birth.
    Summary · context
    Three groups received an intraperitoneal injection of OT, OTA, or isotonic saline.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In female prairie voles, a neonatal oxytocin injection decreased mating bout frequency in adulthood versus saline and handled controls.

    In plain wordsIn female prairie voles, oxytocin injected after birth led to fewer mating bouts in adulthood than saline or handling alone.

    Peptide
    Oxytocin
    Outcome
    DecreaseMating bout frequency in adult females
    Study

    prairie volen: not reported in source

    Comparator
    Saline and handled controls
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · intraperitonealAs given in this study (prairie vole).

    Source sentences

    Summary
    OT and OTA treatment decreased mating bout frequency compared to saline and handled controls
    2 context sentences
    Summary · context
    To test this hypothesis, female prairie voles (Microtus ochrogaster) received one of four treatments within 24 h of birth.
    Summary · context
    Three groups received an intraperitoneal injection of OT, OTA, or isotonic saline.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:51 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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