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Study · Animal study (in vivo) · mouse · 2004

3 results

[Pharmacological correction of memory impairment caused by a complex extremal action in mice with bilateral ligation of common carotid arteries].

Iasnetsov VV, Ivanov IuV

Eksperimental'naia i klinicheskaia farmakologiia1 Sept 2004

PMID15559625 (opens in a new tab)PepBankPUB-15559625
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In mice with bilateral ligation of the common carotid arteries, semax significantly increased survival.

    In plain wordsIn mice with blocked neck arteries, semax increased survival.

    Peptide
    Semax
    Outcome
    IncreaseSurvival after bilateral carotid ligation
    Study

    mousen: not reported in source

    White mongrel male mice with bilateral ligation of common carotid arteries
    Outcome group
    Mortality · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Semax and mexidol significantly increase the survival of white mongrel male mice upon bilateral ligation of common carotid arteries.
    1 context sentence
    Title · context
    [Pharmacological correction of memory impairment caused by a complex extremal action in mice with bilateral ligation of common carotid arteries].
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In ligated mice under a complex extremal action, semax virtually completely prevented the development of retrograde amnesia.

    In plain wordsIn mice with blocked neck arteries under severe stress, semax almost fully prevented memory loss.

    Peptide
    Semax
    Outcome
    DecreaseRetrograde amnesia development
    Study

    mousen: not reported in source

    White mongrel male mice with bilateral ligation of common carotid arteries
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Semax virtually completely prevented retrograde amnesia development in ligated mice under conditions of a complex extremal action (emaciating swim in cold water with simultaneous wheel rotation) and increased the lifetime of these animals in altitude test chamber.
    1 context sentence
    Title · context
    [Pharmacological correction of memory impairment caused by a complex extremal action in mice with bilateral ligation of common carotid arteries].
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In ligated mice, semax increased the lifetime of the animals in an altitude test chamber.

    In plain wordsIn mice with blocked neck arteries, semax lengthened survival time in a low-oxygen altitude chamber.

    Peptide
    Semax
    Outcome
    IncreaseLifetime in altitude test chamber
    Study

    mousen: not reported in source

    White mongrel male mice with bilateral ligation of common carotid arteries
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Semax virtually completely prevented retrograde amnesia development in ligated mice under conditions of a complex extremal action (emaciating swim in cold water with simultaneous wheel rotation) and increased the lifetime of these animals in altitude test chamber.
    1 context sentence
    Title · context
    [Pharmacological correction of memory impairment caused by a complex extremal action in mice with bilateral ligation of common carotid arteries].

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

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