Skip to content

Study · Non-randomized trial · n = 7 · 2005

2 results

Testicular anti-mullerian hormone secretion is stimulated by recombinant human FSH in patients with congenital hypogonadotropic hypogonadism.

Young J, Chanson P, Salenave S, Noël M, Brailly S, O'Flaherty M, Schaison G, Rey R

The Journal of clinical endocrinology and metabolism9 Nov 2004Cited by 105 (Europe PMC)

PMID15536161 (opens in a new tab)DOI10.1210/jc.2004-0542 (opens in a new tab)PepBankPUB-15536161
Publisher pagePubMedAsk about this study
Jump to 2 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In patients with congenital hypogonadotropic hypogonadism, adding hCG to rhFSH dramatically suppressed AMH secretion compared with rhFSH alone.

    In plain wordsIn patients with congenital hypogonadotropic hypogonadism, adding hCG suppressed AMH secretion compared with FSH alone.

    Peptide
    hCG (human chorionic gonadotropin)
    Outcome
    DecreaseAMH secretion
    Study

    n = 7

    Comparator
    rhFSH alone
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    1500 UI twice a week · im · 2 monthsAs given in this study (human).

    Source sentences

    Summary
    However, in contrast to rhFSH alone, the combined rhFSH plus hCG stimulation of the testis dramatically suppresses the secretion of AMH and induced a modest but significant reduction of circulating inhibin B levels.
    1 context sentence
    Summary · context
    The patients received daily sc injections of 150 IU rhFSH for 1 month, followed in seven of them by a combined treatment of rhFSH plus human chorionic gonadotropin (hCG; 1500 UI im, twice a week) for 2 months.
  2. 02HumanNon-randomized trialEfficacy outcome

    In patients with congenital hypogonadotropic hypogonadism, adding hCG to rhFSH modestly but significantly reduced circulating inhibin B compared with rhFSH alone.

    In plain wordsIn patients with congenital hypogonadotropic hypogonadism, adding hCG reduced inhibin B compared with FSH alone.

    Peptide
    hCG (human chorionic gonadotropin)
    Outcome
    DecreaseCirculating inhibin B
    Study

    n = 7

    Comparator
    rhFSH alone
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    1500 UI twice a week · im · 2 monthsAs given in this study (human).

    Source sentences

    Summary
    However, in contrast to rhFSH alone, the combined rhFSH plus hCG stimulation of the testis dramatically suppresses the secretion of AMH and induced a modest but significant reduction of circulating inhibin B levels.
    1 context sentence
    Summary · context
    The patients received daily sc injections of 150 IU rhFSH for 1 month, followed in seven of them by a combined treatment of rhFSH plus human chorionic gonadotropin (hCG; 1500 UI im, twice a week) for 2 months.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

PepBank is a research reference. Talk to a doctor before you use any peptide.