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Study · Animal study (in vivo) · rat · 2004

2 results

Feeding response to ghrelin agonist and antagonist in lean and obese Zucker rats.

Beck B, Richy S, Stricker-Krongrad A

Life sciences1 Dec 2004Cited by 48 (Europe PMC)

PMID15530508 (opens in a new tab)DOI10.1016/j.lfs.2004.09.001 (opens in a new tab)PepBankPUB-15530508
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In lean Zucker rats, GHRP‑6 stimulated food intake.

    In plain wordsIn lean Zucker rats, GHRP‑6 increased food intake.

    Peptide
    GHRP-6
    Outcome
    IncreaseFood intake in lean rats
    Study

    ratn: not reported in source

    Lean FA/FA Zucker rats
    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    1 mg/kg · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    GHRP-6 (1 mg/kg I.P, a GHS-R agonist) stimulated food intake in lean but not in obese rats (p < 0.01)
    2 context sentences
    Summary · context
    In the present experiment, we determined the circulating ghrelin levels in 60-week old fa/fa Zucker rats with a well-established obesity (n = 12) and in their lean (FA/FA) counterparts (n = 12).
    Summary · context
    We also tested the feeding response of both groups to intra-peritoneal (I.P.) injection of ghrelin agonist and antagonist.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In obese Zucker rats, GHRP‑6 did not stimulate food intake.

    In plain wordsIn obese Zucker rats, GHRP‑6 did not increase food intake.

    Peptide
    GHRP-6
    Outcome
    No significant changeFood intake in obese rats
    Study

    ratn: not reported in source

    Obese fa/fa Zucker rats
    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    1 mg/kg · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    GHRP-6 (1 mg/kg I.P, a GHS-R agonist) stimulated food intake in lean but not in obese rats (p < 0.01)
    2 context sentences
    Summary · context
    In the present experiment, we determined the circulating ghrelin levels in 60-week old fa/fa Zucker rats with a well-established obesity (n = 12) and in their lean (FA/FA) counterparts (n = 12).
    Summary · context
    We also tested the feeding response of both groups to intra-peritoneal (I.P.) injection of ghrelin agonist and antagonist.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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