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Study · Randomized controlled trial · n = 38 · 2004

3 results

Selective amnesic effects of oxytocin on human memory.

Heinrichs M, Meinlschmidt G, Wippich W, Ehlert U, Hellhammer DH

Physiology & behavior1 Oct 2004Cited by 126 (Europe PMC)

PMID15501488 (opens in a new tab)DOI10.1016/j.physbeh.2004.07.020 (opens in a new tab)PepBankPUB-15501488
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In healthy men, a single dose of intranasal oxytocin impaired recall performance compared with placebo in the cued recall test, irrespective of word meaning.

    In plain wordsIn healthy men, a single oxytocin nasal dose led to worse word recall than placebo.

    Peptide
    Oxytocin
    Outcome
    DecreaseCued recall performance
    Study

    n = 38

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    24 IU · intranasal · single doseAs given in this study (human).

    Source sentences

    Summary
    Oxytocin significantly impaired recall performance as compared with placebo treatment irrespective of the meaning of words in the cued recall test.
    2 context sentences
    Summary · context
    The purpose of this study was to investigate the effect of a single dose of intranasal oxytocin on implicit and explicit memory in humans.
    Summary · context
    In a placebo-controlled, double-blind study, 38 healthy men were randomly assigned to receive intranasal oxytocin (24 IU) or placebo 50 min before the study phase (incidental learning).
  2. 02HumanRandomized controlled trialEfficacy outcome

    In healthy men, intranasal oxytocin impaired the overall generation of associated target words with reproduction-relevant meaning compared with placebo.

    In plain wordsIn healthy men, oxytocin led to fewer associated words with reproduction meaning than placebo.

    Peptide
    Oxytocin
    Outcome
    DecreaseGeneration of associated target words with reproduction-related meaning (implicit conceptual test)
    Study

    n = 38

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    24 IU · intranasal · single doseAs given in this study (human).

    Source sentences

    Summary
    In the implicit conceptual test, characterized by a deepened information processing, compared with placebo, oxytocin significantly impaired only the overall generation of associated target words with reproduction relevant meaning
    2 context sentences
    Summary · context
    The purpose of this study was to investigate the effect of a single dose of intranasal oxytocin on implicit and explicit memory in humans.
    Summary · context
    In a placebo-controlled, double-blind study, 38 healthy men were randomly assigned to receive intranasal oxytocin (24 IU) or placebo 50 min before the study phase (incidental learning).
  3. 03HumanRandomized controlled trialEfficacy outcome

    In healthy men, intranasal oxytocin and placebo did not differ significantly in the generation of associated target words with neutral meaning.

    In plain wordsIn healthy men, oxytocin and placebo gave no clear difference in generating words with neutral meaning.

    Peptide
    Oxytocin
    Outcome
    No significant changeGeneration of associated target words with neutral meaning (implicit conceptual test)
    Study

    n = 38

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    24 IU · intranasal · single doseAs given in this study (human).

    Source sentences

    Summary
    whereas no significant difference between oxytocin and placebo was obtained for neutral words.
    2 context sentences
    Summary · context
    The purpose of this study was to investigate the effect of a single dose of intranasal oxytocin on implicit and explicit memory in humans.
    Summary · context
    In a placebo-controlled, double-blind study, 38 healthy men were randomly assigned to receive intranasal oxytocin (24 IU) or placebo 50 min before the study phase (incidental learning).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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