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Study · Animal study (in vivo) · chicken · 2004

5 results

[Effect of epitalon on the immunity and hemostasis in hypophysectomized chicken and old hens].

Kuznik BI, Pateiuk AV, Khavinson VKh, Malinin VV

Advances in gerontology = Uspekhi gerontologii1 Jan 2004Cited by 2 (Europe PMC)

PMID15490730 (opens in a new tab)PepBankPUB-15490730

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In hypophysectomized chickens and old hens, epitalon largely eliminated the cellular immunity disturbances.

    In plain wordsIn hypophysectomized chickens and old hens, epitalon largely removed the disturbances of cellular immunity.

    Peptide
    Epitalon
    Outcome
    Not applicableCellular immunity disturbance
    Study

    chickenn: not reported in source

    Neonatally hypophysectomized chickens and old hens
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Administration of Epitalon (Ala-Glu-Asp-Gly) to a large extent eliminates revealed shifts.
    1 context sentence
    Summary · context
    Neonatal hypophysectomy in chicken, as well as that in old hen has been established to entail in 1,5 months after surgery cellular and humoral immunity disturbances, pronounced hypercoagulation and fibrinolysis depression.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In hypophysectomized chickens and old hens, epitalon largely eliminated the humoral immunity disturbances.

    In plain wordsIn hypophysectomized chickens and old hens, epitalon largely removed the disturbances of humoral immunity.

    Peptide
    Epitalon
    Outcome
    Not applicableHumoral immunity disturbance
    Study

    chickenn: not reported in source

    Neonatally hypophysectomized chickens and old hens
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Administration of Epitalon (Ala-Glu-Asp-Gly) to a large extent eliminates revealed shifts.
    1 context sentence
    Summary · context
    Neonatal hypophysectomy in chicken, as well as that in old hen has been established to entail in 1,5 months after surgery cellular and humoral immunity disturbances, pronounced hypercoagulation and fibrinolysis depression.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In hypophysectomized chickens and old hens, epitalon largely eliminated the hypercoagulation.

    In plain wordsIn hypophysectomized chickens and old hens, epitalon largely removed the excess blood clotting tendency.

    Peptide
    Epitalon
    Outcome
    DecreaseHypercoagulation
    Study

    chickenn: not reported in source

    Neonatally hypophysectomized chickens and old hens
    Outcome group
    Cardiovascular events · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Administration of Epitalon (Ala-Glu-Asp-Gly) to a large extent eliminates revealed shifts.
    1 context sentence
    Summary · context
    Neonatal hypophysectomy in chicken, as well as that in old hen has been established to entail in 1,5 months after surgery cellular and humoral immunity disturbances, pronounced hypercoagulation and fibrinolysis depression.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In hypophysectomized chickens and old hens, epitalon largely eliminated the depression of fibrinolysis, so fibrinolysis recovered.

    In plain wordsIn hypophysectomized chickens and old hens, epitalon largely restored clot breakdown.

    Peptide
    Epitalon
    Outcome
    IncreaseFibrinolysis
    Study

    chickenn: not reported in source

    Neonatally hypophysectomized chickens and old hens
    Outcome group
    Cardiovascular events · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Administration of Epitalon (Ala-Glu-Asp-Gly) to a large extent eliminates revealed shifts.
    1 context sentence
    Summary · context
    Neonatal hypophysectomy in chicken, as well as that in old hen has been established to entail in 1,5 months after surgery cellular and humoral immunity disturbances, pronounced hypercoagulation and fibrinolysis depression.
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    The epitalon effect was stronger in neonatally hypophysectomized chickens than in old hens.

    In plain wordsThe epitalon effect was stronger in chickens that lost the pituitary gland at birth than in old hens.

    Peptide
    Epitalon
    Outcome
    Not applicableSize of the epitalon effect in neonatally hypophysectomized chickens versus old hens
    Study

    chickenn: not reported in source

    Neonatally hypophysectomized chickens and old hens
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    This effect appeared to be stronger in neonatally hypophysectomized chicken than in old hens.
    1 context sentence
    Summary · context
    Neonatal hypophysectomy in chicken, as well as that in old hen has been established to entail in 1,5 months after surgery cellular and humoral immunity disturbances, pronounced hypercoagulation and fibrinolysis depression.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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