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Study · Animal study (in vivo) · mouse · 2004

2 results

[The pineal gland's peptides factors and the rhythms of functions of the thymus and bone marrow in animals during aging].

Labunets IF, Butenko GM, Dragunova VA, Magdich LV, Kopylova GV, Rodnichenko AE, Mikhal'skiĭ SA, Khavinson VKh, Azarskova MV, Maksiuk TV

Advances in gerontology = Uspekhi gerontologii1 Jan 2004Cited by 2 (Europe PMC)

PMID15490729 (opens in a new tab)PepBankPUB-15490729
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Summary

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Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In old CBA mice, epithalon decreased the amount of CFC-F in bone marrow in autumn.

    In plain wordsIn old mice, epithalon lowered the amount of bone marrow stromal precursor cells in autumn.

    Peptide
    Epitalon
    Outcome
    DecreaseStromal precursor cell (CFC-F) amount in bone marrow in autumn
    Study

    mousen: not reported in source

    Old CBA mice, bone marrow
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Epithalon also diminished of CFC-GM and CFC-F amount in old mice in autumn.
    1 context sentence
    Summary · context
    It was investigated the influence of pineal peptides on the aging changes both circadian rhythm of thymic serum factor (FTS) titer in male rats Wistar and circannual rhythms of FTS, the amount of stromal cells-precurcors (CFC-F), granulocyte-macrophage cells-precurcors (CFC-GM), CD4+, Mac-1+ and CD1…
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In old CBA mice, epithalon decreased the amount of CFC-GM in bone marrow in autumn.

    In plain wordsIn old mice, epithalon lowered the amount of bone marrow granulocyte-macrophage precursor cells in autumn.

    Peptide
    Epitalon
    Outcome
    DecreaseGranulocyte-macrophage precursor cell (CFC-GM) amount in bone marrow in autumn
    Study

    mousen: not reported in source

    Old CBA mice, bone marrow
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Epithalon also diminished of CFC-GM and CFC-F amount in old mice in autumn.
    1 context sentence
    Summary · context
    It was investigated the influence of pineal peptides on the aging changes both circadian rhythm of thymic serum factor (FTS) titer in male rats Wistar and circannual rhythms of FTS, the amount of stromal cells-precurcors (CFC-F), granulocyte-macrophage cells-precurcors (CFC-GM), CD4+, Mac-1+ and CD1…

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    21 Oct 2026, 12:50 UTC

    Study data updated · source update from Europe PMC

  2. Version 2

    12 Oct 2026, 17:28 UTC

    Study results updated

  3. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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