In eukaryotic cells expressing the chicken MC4 receptor, the synthetic ligand MTII was a potent agonist.
In plain wordsIn cells carrying the chicken MC4 receptor, MTII was a potent agonist.
- Peptide
- Melanotan II
- Outcome
- Not applicableAgonist potency at chicken MC4 receptor
- Study
chickenn: not reported in source
Chicken MC4 receptor expressed in eukaryotic cells- Outcome group
- Receptor activity and mechanism · Pharmacology
- Studied dose
- Dose not stated
Source sentences
The synthetic ligand MTII was found to be a potent agonist
1 context sentence(design, population, supporting numbers)
2 To clarify the pharmacological impact of ligands acting in the MC system, we expressed the chicken MC1, MC2, MC3, MC4 and MC5 (cMC1-5) receptors in eukaryotic cells and performed comprehensive pharmacological characterization of the potency of endogenous and synthetic melanocortin peptides.