In L6 myotubes, AICAR markedly increased palmitate oxidation compared with PBS control.
In plain wordsIn cells, AICAR increased palmitate oxidation compared with PBS control.
- Peptide
- AICAR (acadesine)
- Outcome
- IncreasePalmitate oxidation
- Study
n: not reported in source
L6 myotubes- Comparator
- PBS control
- Outcome group
- Lipids · Metabolic and weight
- Studied dose
- Dose not stated
Source sentences
Both IL-6 and AICAR markedly increased (P < 0.05) oxidation of [(14)C]palmitate compared with Control.
1 context sentence(design, population, supporting numbers)
To assess whether IL-6 increases fat oxidation, L6 myotubes were treated with PBS (Control), IL-6, or AICAR, a compound known to increase lipid oxidation.