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Study · Animal study (in vivo) · rat · 2004

2 results

Structural-functional organization of neurons in the cerebral cortex of rats with different levels of resistance to emotional stress in conditions of exposure to delta sleep-inducing peptide.

Bogolepov NN, Popova EN, Koplik EV, Krivitskaya GN, Sudakov KV

Neuroscience and behavioral physiology1 Jul 2004Cited by 2 (Europe PMC)

PMID15368909 (opens in a new tab)DOI10.1023/b:neab.0000028293.62205.5f (opens in a new tab)PepBankPUB-15368909
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In stressed Wistar rats, ischemically altered cells in layer V of the sensorimotor cortex were not seen in any group after DSIP given before stress.

    In plain wordsIn stressed rats given DSIP before stress, damaged brain cells of one type were not seen in the cortex.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseIschemically altered neurons in sensorimotor cortex
    Study

    ratn: not reported in source

    Wistar rats with different resistance to emotional stress
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    After administration of DSIP before stress, ischemically altered cells were not seen in any group
    2 context sentences
    Summary · context
    Wistar rats with different levels of resistance to emotional stress (ES) were subjected to stress and brain sections stained with Nissl cresyl violet were used for quantitative analysis of the structural organization of neurons in layer V of the sensorimotor cortex.
    Summary · context
    Some animals received delta sleep-inducing peptide (DSIP) 1 h before stress.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In stressed Wistar rats given DSIP before stress, the reduction of extremely hyperchromic neurons was smaller in stress-susceptible rats than in stress-resistant rats.

    In plain wordsIn stressed rats given DSIP, a type of cortical neuron fell by less in stress-susceptible rats than in stress-resistant rats.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Direction not reportedExtremely hyperchromic neurons in sensorimotor cortex
    Study

    ratn: not reported in source

    Wistar rats with different resistance to emotional stress
    Comparator
    ES-resistant rats
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    the level of reduction of extremely hyperchromic neurons was smaller in ES-susceptible rats than in ES-resistant rats.
    2 context sentences
    Summary · context
    Wistar rats with different levels of resistance to emotional stress (ES) were subjected to stress and brain sections stained with Nissl cresyl violet were used for quantitative analysis of the structural organization of neurons in layer V of the sensorimotor cortex.
    Summary · context
    Some animals received delta sleep-inducing peptide (DSIP) 1 h before stress.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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