Skip to content

Study · Not a test of the peptide alone · 2004

3 results

Oxytocin and estrogen receptor alpha and beta knockout mice provide discriminably different odor cues in behavioral assays.

Kavaliers M, Agmo A, Choleris E, Gustafsson JA, Korach KS, Muglia LJ, Pfaff DW, Ogawa S

Genes, brain, and behavior1 Aug 2004Cited by 22 (Europe PMC)

PMID15307217 (opens in a new tab)DOI10.1111/j.1601-183x.2004.00068.x (opens in a new tab)PepBankPUB-15307217
Publisher pagePubMedAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 01AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Other

    In mice, females chose the urine odors of oxytocin wildtype males over those of oxytocin knockout males.

    In plain wordsIn mice, females preferred the urine odor of normal males over that of males lacking the oxytocin gene.

    Peptide
    Oxytocin
    Outcome
    Not applicableFemale choice of urine odors of OTWT versus OTKO males
    Study

    Mousen: not reported in source

    Oxytocin knockout male mice; Swiss-Webster female receivers
    Comparator
    Wildtype littermates
    Outcome group
    Social behavior and cognition · Nervous system and cognition

    Source sentences

    Summary
    Females showed marked initial choices of the urine odors of OTWT and betaERWT males over those of OTKOand PERKO males, and alphaERKO males over alphaERWT males.
    1 context sentence
    Summary · context
    In this study we demonstrate that these gene knockout mice also provide discriminably different social stimuli in behavioral assays.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  2. 02AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Other

    In mice, the urine odors of oxytocin knockout males induced aversive, analgesic responses in females, and wildtype odors had no significant effect.

    In plain wordsIn mice, odors of males lacking the oxytocin gene caused pain-reducing aversive responses in females; odors of normal males did not.

    Peptide
    Oxytocin
    Outcome
    Not applicableAversive analgesic response to OTKO male odors
    Study

    Mousen: not reported in source

    Oxytocin knockout male mice; Swiss-Webster female receivers
    Comparator
    Wildtype littermates
    Outcome group
    Pain · Nervous system and cognition

    Source sentences

    Summary
    The odors of OTKO and betaERKO males also induced aversive, analgesic responses, with the odors of WTs having no significant effects.
    1 context sentence
    Summary · context
    In this study we demonstrate that these gene knockout mice also provide discriminably different social stimuli in behavioral assays.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  3. 03AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Other

    In mice, females showed significantly greater analgesia to odors of stressed oxytocin knockout males than to those of stressed wildtype males.

    In plain wordsIn mice, females showed more pain-reducing responses to odors of stressed males lacking the oxytocin gene than to odors of stressed normal males.

    Peptide
    Oxytocin
    Outcome
    Not applicableAnalgesia to odors of restraint-stressed OTKO males
    Study

    Mousen: not reported in source

    Oxytocin knockout male mice; Swiss-Webster female receivers
    Comparator
    Wildtype littermates
    Outcome group
    Anxiety and mood · Nervous system and cognition

    Source sentences

    Summary
    The odors of restraint stressed WT and KO males also elicited analgesia with, again, females dis-playing significantly greater responses to the odors of stressed OTKO and betaERKO males than their WTs
    1 context sentence
    Summary · context
    In this study we demonstrate that these gene knockout mice also provide discriminably different social stimuli in behavioral assays.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:52 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.