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Study · Measured the body's own peptide · 2004

1 result

The effect of changes in arterial PCO2 on neuroendocrine function in man.

Leach RM, Forsling ML

Experimental physiology16 Mar 2004Cited by 7 (Europe PMC)

PMID15123564 (opens in a new tab)DOI10.1113/expphysiol.2003.026682 (opens in a new tab)PepBankPUB-15123564
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelNon-randomized trialOther

    In ventilated ICU patients in late recovery, circulating oxytocin concentrations increased with increasing arterial PCO2.

    In plain wordsIn ICU patients, the body's own oxytocin levels in blood rose as carbon dioxide in arterial blood rose.

    Peptide
    Oxytocin
    Outcome
    IncreaseCirculating oxytocin with changing arterial PCO2
    Study

    n = 20

    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Circulating concentrations of growth hormone and oxytocin increased with increasing P(a,CO(2)).
    2 context sentences
    Summary · context
    The study was performed in 20 ventilated ICU patients in the late recovery phase of their illness.
    Summary · context
    Control blood samples were taken and the alveolar ventilation was then adjusted to allow the P(a,CO(2)) increase or decrease for a period of 3 h, during which time further blood samples were taken for the determination, by radioimmmunoassy of vasopressin, oxytocin, growth hormone and cortisol.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:51 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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