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Study · Animal study (in vivo) · prairie vole · 2004

2 results

Sex differences and developmental effects of manipulations of oxytocin on alloparenting and anxiety in prairie voles.

Bales KL, Pfeifer LA, Carter CS

Developmental psychobiology1 Mar 2004Cited by 81 (Europe PMC)

PMID14994263 (opens in a new tab)DOI10.1002/dev.10165 (opens in a new tab)PepBankPUB-14994263
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In female prairie voles, neonatal oxytocin or oxytocin antagonist did not significantly change behaviour later in life.

    In plain wordsIn female prairie voles, a newborn injection of oxytocin or an oxytocin blocker did not significantly change later behaviour.

    Peptide
    Oxytocin
    Outcome
    No significant changeFemale alloparental behaviour and elevated plus maze behaviour after neonatal treatments
    Study

    prairie volen: not reported in source

    Neonatal prairie voles tested as adults
    Comparator
    Saline or handling only
    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    Dose not stated · intraperitonealAs given in this study (prairie vole).

    Source sentences

    Summary
    Female behavior was not significantly changed as a function of neonatal treatments.
    2 context sentences
    Summary · context
    Prairie voles (Microtus ochrogaster), a cooperatively breeding species, were selected for this study.
    Summary · context
    On neonatal Day 1, pups received an ip injection of oxytocin or oxytocin antagonist, or were controls, receiving either saline or handling only.

Studies that did not test the peptide alone1

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 02AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Efficacy outcome

    In male prairie voles, neonatal treatment with an oxytocin antagonist was associated with reduced parental care, especially during the first exposure to pups on Day 21.

    In plain wordsIn male prairie voles, a newborn dose of an oxytocin blocker was linked to less parental care later. This is about the blocker.

    Peptide
    Oxytocin
    Outcome
    DecreaseParental care in males after neonatal oxytocin antagonist
    Study

    prairie volen: not reported in source

    Neonatal prairie voles tested as adults
    Comparator
    Saline or handling only
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    In males, neonatal treatment with oxytocin antagonist was associated with reductions in parental care, especially during the initial exposure to pups on Day 21.
    2 context sentences
    Summary · context
    Prairie voles (Microtus ochrogaster), a cooperatively breeding species, were selected for this study.
    Summary · context
    On neonatal Day 1, pups received an ip injection of oxytocin or oxytocin antagonist, or were controls, receiving either saline or handling only.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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