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Study · Not a test of the peptide alone · 2004

3 results

Evaluation of the reproducibility of the GHRH plus GHRP-6 test of growth hormone reserve in adults.

Popovic V, Pekic S, Micic D, Damjanovic S, Marikovic J, Simic M, Dieguez C, Casanueva FF

Clinical endocrinology1 Feb 2004Cited by 9 (Europe PMC)

PMID14725679 (opens in a new tab)DOI10.1046/j.1365-2265.2003.01955.x (opens in a new tab)PepBankPUB-14725679
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHRP-6.

  1. 01HumanNot a test of GHRP-6 aloneNon-randomized trialOther

    In healthy adults, repeated GHRH plus GHRP‑6 tests produced reproducible group GH peaks.

    In plain wordsIn healthy adults, the combined GHRH plus GHRP‑6 test gave reproducible growth hormone peaks.

    Peptide
    GHRP-6
    Outcome
    Not applicableGH peaks across repeated tests
    Study

    n = 17

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Measurements

    GH peak
    46 micro g/l
    Test 1
    GH peak
    48.4 micro g/l
    Test 2
    GH peak
    50.1 micro g/l
    Test 3
    GH peak
    52.9 micro g/l
    Test 4

    Source sentences

    Summary
    As a group, the subjects showed high reproducibility after the four tests, with GH peaks of 46.0 +/- 5.1; 48.4 +/- 6.4; 50.1 +/- 5.4 and 52.9 +/- 5.8 micro g/l, respectively (1 micro g/l = 3 mU/l).
    2 context sentences
    Summary · context
    Seventeen healthy subjects were challenged with GHRH plus GHRP-6 (1 micro g/kg i.v.).
    Summary · context
    All subjects underwent four tests on different days separated by at least 2 months.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  2. 02HumanNot a test of GHRP-6 aloneNon-randomized trialOther

    In healthy adults, GH peaks after combined GHRH plus GHRP‑6 correlated between the first test and subsequent tests.

    In plain wordsIn healthy adults, growth hormone peaks after the combined test correlated across repeat tests.

    Peptide
    GHRP-6
    Outcome
    Not applicableIndividual test reproducibility
    Study

    n = 17

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Measurements

    Correlation coefficient
    0.729 R
    Tests 1 and 2
    Correlation coefficient
    0.71 R
    Tests 1 and 3
    Correlation coefficient
    0.683 R
    Tests 1 and 4

    Source sentences

    Summary
    Individually analysed, the reproducibility was good, and the regression analysis showed a correlation between tests 1 and 2 of R = 0.729, P < 0.0009, between tests 1 and 3 of R = 0.710, P < 0.001, and between tests 1 and 4 of R = 0.683, P < 0.002.
    3 context sentences
    Summary · context
    Under mathematical analysis, the multiple correlation coefficient analysis, analysis of variance (anova) with repeated measurements, repeatability index, the simplest coefficient of variation and the intraclass correlation coefficient (ICC) all unambiguously showed that the GHRH + GHRP-6 test was reproducible.
    Summary · context
    Seventeen healthy subjects were challenged with GHRH plus GHRP-6 (1 micro g/kg i.v.).
    Summary · context
    All subjects underwent four tests on different days separated by at least 2 months.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  3. 03HumanNot a test of GHRP-6 aloneNon-randomized trialOther

    In healthy adults, repeated GHRH plus GHRP‑6 tests did not change biochemical diagnosis and produced no false-positive values.

    In plain wordsIn healthy adults, repeated combined tests did not change the diagnosis or produce false-positive results.

    Peptide
    GHRP-6
    Outcome
    No significant changeBiochemical diagnosis reproducibility
    Study

    n = 17

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    Furthermore, the repeated tests did not alter the biochemical diagnosis of the subjects, with absence of false-positive values.
    2 context sentences
    Summary · context
    Seventeen healthy subjects were challenged with GHRH plus GHRP-6 (1 micro g/kg i.v.).
    Summary · context
    All subjects underwent four tests on different days separated by at least 2 months.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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