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Study · Not a test of the peptide alone · 2004

5 results

Ventral striatopallidal oxytocin and vasopressin V1a receptors in the monogamous prairie vole (Microtus ochrogaster).

Lim MM, Murphy AZ, Young LJ

The Journal of comparative neurology1 Jan 2004Cited by 128 (Europe PMC)

PMID14689486 (opens in a new tab)DOI10.1002/cne.10973 (opens in a new tab)PepBankPUB-14689486
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone5

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 01AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Other

    In prairie voles, destruction of ventral striatal dopaminergic terminals with 6-hydroxydopamine did not alter oxytocin receptor binding.

    In plain wordsIn prairie voles, destroying dopamine terminals with 6-hydroxydopamine did not alter oxytocin receptor binding.

    Peptide
    Oxytocin
    Outcome
    No significant changeOxytocin receptor binding after dopaminergic terminal destruction
    Study

    prairie volen: not reported in source

    nucleus accumbens after 6-hydroxydopamine infusion
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    Furthermore, destruction of ventral striatal dopaminergic terminals with 6-hydroxydopamine infusions into the nucleus accumbens did not alter OTR binding.
    1 context sentence
    Summary · context
    To delineate more clearly the neuroanatomical boundaries of the OTR and V1aR fields in this species, we compared OTR and V1aR binding in adjacent brain sections and also with markers that delineate neuroanatomical boundaries in the ventral forebrain.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  2. 02LabNot a test of Oxytocin aloneEx vivo tissueOther

    In prairie voles, oxytocin receptor binding overlapped with substance P mRNA and preproenkephalin mRNA, markers for the shell and core of the nucleus accumbens.

    In plain wordsIn lab tests of prairie vole brain sections, oxytocin receptor binding overlapped with nucleus-accumbens markers.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin receptor binding distribution
    Study

    prairie volen: not reported in source

    adjacent ventral forebrain sections
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    OTR binding displayed an overlapping distribution with substance P mRNA and preproenkephalin mRNA, both markers for the shell and core of the nucleus accumbens.
    1 context sentence
    Summary · context
    To delineate more clearly the neuroanatomical boundaries of the OTR and V1aR fields in this species, we compared OTR and V1aR binding in adjacent brain sections and also with markers that delineate neuroanatomical boundaries in the ventral forebrain.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  3. 03LabNot a test of Oxytocin aloneEx vivo tissueOther

    In prairie voles, oxytocin receptor mRNA was restricted to the nucleus accumbens.

    In plain wordsIn lab tests of prairie vole brain tissue, oxytocin receptor mRNA was restricted to the nucleus accumbens.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin receptor mRNA location
    Study

    prairie volen: not reported in source

    ventral forebrain sections
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    OTR and V1aR mRNA were also restricted within the nucleus accumbens and ventral pallidum, respectively.
    1 context sentence
    Summary · context
    To delineate more clearly the neuroanatomical boundaries of the OTR and V1aR fields in this species, we compared OTR and V1aR binding in adjacent brain sections and also with markers that delineate neuroanatomical boundaries in the ventral forebrain.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  4. 04LabNot a test of Oxytocin aloneEx vivo tissueOther

    In prairie voles, oxytocin-immunoreactive fibers were present in the nucleus accumbens.

    In plain wordsIn lab tests of prairie vole brain tissue, oxytocin-immunoreactive fibers were present in the nucleus accumbens.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin-immunoreactive fibers in nucleus accumbens
    Study

    prairie volen: not reported in source

    ventral forebrain sections
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    Immunocytochemical analysis of oxytocin and vasopressin in the ventral forebrain demonstrated the presence of oxytocin-immunoreactive fibers in the nucleus accumbens
    1 context sentence
    Summary · context
    To delineate more clearly the neuroanatomical boundaries of the OTR and V1aR fields in this species, we compared OTR and V1aR binding in adjacent brain sections and also with markers that delineate neuroanatomical boundaries in the ventral forebrain.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  5. 05LabNot a test of Oxytocin aloneEx vivo tissueOther

    In prairie voles, oxytocin fiber density in the ventral forebrain showed no sex difference.

    In plain wordsIn lab tests of prairie vole brain tissue, oxytocin-immunoreactive fiber density showed no difference between males and females.

    Peptide
    Oxytocin
    Outcome
    No significant changeSex difference in oxytocin fiber density
    Study

    prairie volen: not reported in source

    ventral forebrain sections
    Comparator
    Female voles
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    Immunocytochemical analysis of oxytocin and vasopressin in the ventral forebrain demonstrated the presence of oxytocin-immunoreactive fibers in the nucleus accumbens and vasopressin-immunoreactive fibers in the ventral pallidum, with males showing a greater density of vasopressin fibers than females…
    1 context sentence
    Summary · context
    To delineate more clearly the neuroanatomical boundaries of the OTR and V1aR fields in this species, we compared OTR and V1aR binding in adjacent brain sections and also with markers that delineate neuroanatomical boundaries in the ventral forebrain.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:51 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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