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Study · Not a test of the peptide alone · 2004

2 results

Formation equilibria of nickel complexes with glycyl-histidyl-lysine and two synthetic analogues.

Conato C, Kozłowski H, Swiatek-Kozłowska J, Młynarz P, Remelli M, Silvestri S

Journal of inorganic biochemistry1 Jan 2004Cited by 7 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, GHK (glycyl-L-histidyl-L-lysine) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHK (glycyl-L-histidyl-L-lysine).

  1. 01LabNot a test of GHK (glycyl-L-histidyl-L-lysine) aloneIn vitro (cell-free)Mechanism

    In nickel complex experiments, GHK showed evidence of tetrameric species formation.

    In plain wordsIn lab tests, GHK showed evidence of tetramer formation with nickel.

    Outcome
    Not applicableTetramer formation
    Study

    n: not reported in source

    nickel-GHK complexes
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    Evidences on the formation of tetrameric species with the first ligand are shown.
    2 context sentences
    Summary · context
    Complex-formation equilibria between the Ni(II) ion and the natural tripeptide glycyl-L-histidyl-L-lysine have been investigated.
    Summary · context
    Different experimental techniques have been employed: potentiometry, calorimetry, visible spectrophotometry and CD spectroscopy.

    In this study, GHK (glycyl-L-histidyl-L-lysine) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHK (glycyl-L-histidyl-L-lysine).

  2. 02LabNot a test of GHK (glycyl-L-histidyl-L-lysine) aloneIn vitro (cell-free)Mechanism

    In nickel-GHK complexes, the lysine side-chain amino group did not participate in metal coordination.

    In plain wordsIn lab tests, the lysine side-chain amino group did not coordinate the metal in GHK complexes.

    Outcome
    Not applicableLysine side-chain coordination
    Study

    n: not reported in source

    nickel-GHK complexes
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    No involvement of the side-chain amino group of lysine residue in metal ion coordination was found.
    2 context sentences
    Summary · context
    Complex-formation equilibria between the Ni(II) ion and the natural tripeptide glycyl-L-histidyl-L-lysine have been investigated.
    Summary · context
    Different experimental techniques have been employed: potentiometry, calorimetry, visible spectrophotometry and CD spectroscopy.

    In this study, GHK (glycyl-L-histidyl-L-lysine) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHK (glycyl-L-histidyl-L-lysine).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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