In rat pups, a single intranasal administration of Semax to pregnant females prevented hypoxia-related changes in biogenic amine content in the CNS during postnatal ontogeny.
In plain wordsIn rats, Semax given once to pregnant mothers prevented changes in brain amine levels in their pups.
- Peptide
- Semax
- Outcome
- Direction not reportedBiogenic amine content in offspring CNS
- Study
ratn: not reported in source
Progestational hypobaric hypoxia, offspring of treated pregnant females- Outcome group
- Neuroprotection · Nervous system and cognition
- Studied dose
- Dose not stated · intranasal · single administrationAs given in this study (rat).
Source sentences
Single intranasal administration of Semax heptapeptides and beta-casomorphine-7 to pregnant females prevented changes in the content of biogenic amines in CNS of the offspring during postnatal ontogeny.
1 context sentence(design, population, supporting numbers)
We studied the effect of exposure to acute hypobaric hypoxia in the progestational period on the content of biogenic amines in the brainstem and cerebral cortex in rat pups of different age.