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Study · Not a test of the peptide alone · 2003

2 results

The role of activity-dependent neuroprotective protein in a mouse model of fetal alcohol syndrome.

Poggi SH, Goodwin K, Hill JM, Brenneman DE, Tendi E, Schinelli S, Abebe D, Spong CY

American journal of obstetrics and gynecology1 Sept 2003Cited by 22 (Europe PMC)

PMID14526315 (opens in a new tab)DOI10.1067/s0002-9378(03)00834-2 (opens in a new tab)PepBankPUB-14526315
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Davunetide was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Davunetide.

  1. 01AnimalNot a test of Davunetide aloneAnimal study (in vivo)Mechanism

    In mouse embryos, peptide pretreatment did not prevent the alcohol-induced increase in ADNP expression.

    In plain wordsIn mice, NAP and SAL pretreatment did not prevent increased embryonic ADNP expression compared with alcohol alone.

    Peptide
    Davunetide
    Outcome
    No significant changeEmbryonic ADNP expression
    Study

    mousen: not reported in source

    Fetal alcohol syndrome
    Comparator
    Alcohol alone
    Outcome group
    Neuroprotection · Nervous system and cognition

    Source sentences

    Summary
    Peptide pretreatment did not prevent the alcohol-induced increase in ADNP in embryo or decidua.
    2 context sentences
    Summary · context
    Peptides NAPVSIPQ (NAP) and SALLRSIPA (SAL), related to activity-dependent neuroprotective protein (ADNP), prevent alcohol-induced damage in a mouse model of FAS.
    Summary · context
    Timed, pregnant C57Bl6/J mice were treated on day 8. Groups were control, alcohol, peptide pretreatment, or peptide alone. Embryo and decidua were harvested at 6 and 24 hours and 10 days.

    In this study, Davunetide was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Davunetide.

  2. 02AnimalNot a test of Davunetide aloneAnimal study (in vivo)Mechanism

    In mouse decidua, peptide pretreatment did not prevent the alcohol-induced increase in ADNP expression.

    In plain wordsIn mice, NAP and SAL pretreatment did not prevent increased decidual ADNP expression compared with alcohol alone.

    Peptide
    Davunetide
    Outcome
    No significant changeDecidual ADNP expression
    Study

    mousen: not reported in source

    Fetal alcohol syndrome
    Comparator
    Alcohol alone
    Outcome group
    Neuroprotection · Nervous system and cognition

    Source sentences

    Summary
    Peptide pretreatment did not prevent the alcohol-induced increase in ADNP in embryo or decidua.
    2 context sentences
    Summary · context
    Peptides NAPVSIPQ (NAP) and SALLRSIPA (SAL), related to activity-dependent neuroprotective protein (ADNP), prevent alcohol-induced damage in a mouse model of FAS.
    Summary · context
    Timed, pregnant C57Bl6/J mice were treated on day 8. Groups were control, alcohol, peptide pretreatment, or peptide alone. Embryo and decidua were harvested at 6 and 24 hours and 10 days.

    In this study, Davunetide was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Davunetide.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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