In male mice with anxiety and depressive syndrome, a preparation of antibodies to DSIP in ultralow doses produced a strong anxiolytic effect, most pronounced in animals with the syndrome.
In plain wordsIn mice with anxiety and depression-like behaviour, antibodies to DSIP in ultralow doses had a strong anxiety-reducing effect.
- Outcome
- DecreaseAnxiety-like behavior in mice with anxiety and depressive syndrome
- Study
mousen: not reported in source
- Outcome group
- Anxiety and mood · Mental health and mood
Source sentences
The preparation produced a strong anxiolytic effect, which was especially pronounced in animals with anxiety and depressive syndrome.
2 context sentences(design, population, supporting numbers)
We studied the effect of antibodies to delta sleep-inducing peptide in ultralow doses on the behavior of male mice with anxiety and depressive syndrome resulting from competitive interactions.
The behavior of animals was studied in the elevated plus-maze, partition, and forced swimming tests.
In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).