In rats with stress-induced anxious depression, a single oral mixture of ultralow-dose antibodies against S100 protein and DSIP was highly effective in all behavioral tests.
In plain wordsIn rats with stress-induced anxiety and depression, a mixture of antibodies to S100 protein and DSIP worked well in all tests.
- Outcome
- Not applicableAnxiety-like behavior in behavioral tests
- Study
ratn: not reported in source
anxious depression after acute stress (unavoidable electrical shock)- Outcome group
- Anxiety and mood · Mental health and mood
Source sentences
High efficiency of the mixture of antibodies against S100 protein and delta sleep-inducing peptide was observed in all tests.
2 context sentences(design, population, supporting numbers)
We studied the effects of single peroral treatment with antibodies against S100 protein and delta sleep-inducing peptide in ultralow doses on behavioral characteristics of rats with anxious depression produced by acute stress (unavoidable electrical shock).
Stress-produced behavioral changes and anxiolytic activity of antibodies were determined using the elevated plus-maze, open field, and tail suspension tests.
In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).