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Study · Animal study (in vivo) · rat · 2003

2 results

Retinoprotective effect of Epithalon in campbell rats of various ages.

Khavinson VKh, Razumovsky MI, Trofimova SV, Razumovskaya AM

Bulletin of experimental biology and medicine1 May 2003Cited by 3 (Europe PMC)

PMID12910293 (opens in a new tab)DOI10.1023/a:1024931812822 (opens in a new tab)PepBankPUB-12910293
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In Campbell rats, Epithalon given to mothers before mating and during pregnancy and to the offspring after birth preserved retinal structure and function for 2 times longer than in control rats.

    In plain wordsIn rats, Epithalon given to mothers and offspring kept the retina intact about 2 times longer than in control rats.

    Peptide
    Epitalon
    Outcome
    IncreasePreservation of retinal structure and function
    Study

    ratn: not reported in source

    Campbell rats
    Comparator
    Control rats
    Outcome group
    Vision and retina · Eye
    Studied dose
    Dose not stated

    Measurements

    Retina preservation period ratio
    2 times
    vs control rats

    Source sentences

    Summary
    After this treatment the morphological structure and functional activity of the retina were preserved for a longer period compared to control rats (by 2 times) and to the animals receiving the peptide only during postnatal ontogeny (by 30%).
    1 context sentence
    Summary · context
    We studied the retinoprotective effect of Epithalon administered to the offspring of Campbell rats during postnatal ontogeny and to mothers before mating and during pregnancy.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In Campbell rats, Epithalon given to mothers and offspring preserved retinal structure and function by 30% longer than in rats given the peptide only after birth.

    In plain wordsIn rats, Epithalon given to mothers and offspring kept the retina intact 30% longer than Epithalon given only after birth.

    Peptide
    Epitalon
    Outcome
    IncreasePreservation of retinal structure and function
    Study

    ratn: not reported in source

    Campbell rats
    Comparator
    Rats given the peptide only during postnatal ontogeny
    Outcome group
    Vision and retina · Eye
    Studied dose
    Dose not stated

    Measurements

    Retina preservation period gain
    30%
    vs peptide only in postnatal ontogeny

    Source sentences

    Summary
    After this treatment the morphological structure and functional activity of the retina were preserved for a longer period compared to control rats (by 2 times) and to the animals receiving the peptide only during postnatal ontogeny (by 30%).
    1 context sentence
    Summary · context
    We studied the retinoprotective effect of Epithalon administered to the offspring of Campbell rats during postnatal ontogeny and to mothers before mating and during pregnancy.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 08:19 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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