In MC4-R promoter GFP transgenic mice, the MC3/4-R agonist MT-II depolarized some GFP-expressing cells.
In plain wordsIn mice, melanotan II depolarized some of the cells that carry the MC4 receptor.
- Peptide
- Melanotan II
- Outcome
- IncreaseDepolarization of GFP-expressing MC4-R cells
- Study
mousen: not reported in source
MC4-R promoter GFP transgenic mice- Outcome group
- Receptor activity and mechanism · Nervous system and cognition
- Studied dose
- Dose not stated
Source sentences
Finally, we have observed that a synthetic MC3/4-R agonist, MT-II, depolarizes some GFP-expressing cells
1 context sentence(design, population, supporting numbers)
To address these issues, we have generated a transgenic mouse line expressing green fluorescent protein (GFP) under the control of the MC4-R promoter, using a modified bacterial artificial chromosome.