[Regulation of the neuronal functional state by ultra low doses of different biologically active substances. Nonspecific effect ].

Terekhova SF, Grechenko TN

Radiatsionnaia biologiia, radioecologiia1 May 2003Cited by 1 (Europe PMC)

PMID12881986PepBankPUB-12881986

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone5

In this study, the peptide was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking the peptide.

01LabNot a test of Noopept (omberacetam) aloneEx vivo tissueActivity measurement
In isolated molluscan neurons, all tested substances, including GVS-111, initiated prolonged neurophysiological responses.
In plain wordsIn lab tests with molluscan neurons, all tested substances, including GVS-111, initiated prolonged nerve responses.
Peptide
Noopept (omberacetam)
Outcome
Direction not reportedProlonged neurophysiological responses
Study
molluscn: not reported in source
Completely isolated molluscan neurons
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Source sentences
Summary
The results demonstrated that all substances had initiated the development of prolonged neurophysiological responses.
2 context sentences(design, population, supporting numbers)
Summary · context
Several substances were used in these experiments: two kinds of synthetic antioxidant, GABA, ethanol, serotonine, DSIP (delta-sleep inducing peptide), antibiotic ruboxil, nootrop GVS-111.
Summary · context
All these substances (0.35 ml) were added single dosing into this chamber with living physiological solution in concentration 10(-15)-10(-27) mol/l.
In this study, Noopept (omberacetam) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Noopept (omberacetam).
Report a problemFND-1288198603
02LabNot a test of Noopept (omberacetam) aloneEx vivo tissueActivity measurement
In isolated molluscan neurons, reaction intensity across tested substances, including GVS-111, did not depend on concentration during contact.
In plain wordsIn lab tests with molluscan neurons, reaction intensity across substances, including GVS-111, did not depend on concentration during contact.
Peptide
Noopept (omberacetam)
Outcome
No significant changeDependence of neuronal reaction intensity on concentration
Study
molluscn: not reported in source
Completely isolated molluscan neurons
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Source sentences
Summary
The intensities of neuronal reactions didn't depend in contact period on the concentration and on the type of substance.
2 context sentences(design, population, supporting numbers)
Summary · context
Several substances were used in these experiments: two kinds of synthetic antioxidant, GABA, ethanol, serotonine, DSIP (delta-sleep inducing peptide), antibiotic ruboxil, nootrop GVS-111.
Summary · context
All these substances (0.35 ml) were added single dosing into this chamber with living physiological solution in concentration 10(-15)-10(-27) mol/l.
In this study, Noopept (omberacetam) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Noopept (omberacetam).
Report a problemFND-1288198604
03LabNot a test of Noopept (omberacetam) aloneEx vivo tissueActivity measurement
In isolated molluscan neurons, reaction intensity across tested substances, including GVS-111, did not depend on substance type during contact.
In plain wordsIn lab tests with molluscan neurons, reaction intensity across substances, including GVS-111, did not depend on substance type during contact.
Peptide
Noopept (omberacetam)
Outcome
No significant changeDependence of neuronal reaction intensity on substance type
Study
molluscn: not reported in source
Completely isolated molluscan neurons
Outcome group
Receptor activity and mechanism · Nervous system and cognition
Source sentences
Summary
The intensities of neuronal reactions didn't depend in contact period on the concentration and on the type of substance.
2 context sentences(design, population, supporting numbers)
Summary · context
Several substances were used in these experiments: two kinds of synthetic antioxidant, GABA, ethanol, serotonine, DSIP (delta-sleep inducing peptide), antibiotic ruboxil, nootrop GVS-111.
Summary · context
All these substances (0.35 ml) were added single dosing into this chamber with living physiological solution in concentration 10(-15)-10(-27) mol/l.
In this study, Noopept (omberacetam) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Noopept (omberacetam).
Report a problemFND-1288198605
04LabNot a test of Delta sleep-inducing peptide (DSIP) aloneIn vitro (cells)Activity measurement
In isolated molluscan neurones, all substances tested at 10(-15)-10(-27) mol/l, DSIP among them, initiated prolonged neurophysiological responses.
In plain wordsIn isolated snail-type neurones, all tested substances, DSIP among them, triggered long-lasting responses at extremely low doses.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
Direction not reportedNeurophysiological responses to ultra-low doses
Study
molluscn: not reported in source
Isolated molluscan neurones
Outcome group
Brain and neuronal activity · Nervous system and cognition
Source sentences
Summary
The results demonstrated that all substances had initiated the development of prolonged neurophysiological responses.
1 context sentence(design, population, supporting numbers)
Summary · context
The isolated neurones were placed into the special chamber.
In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).
Report a problemFND-1288198601
05LabNot a test of Delta sleep-inducing peptide (DSIP) aloneIn vitro (cells)Activity measurement
In isolated molluscan neurones, response intensity did not depend on the concentration or the type of substance, DSIP among them.
In plain wordsIn isolated snail-type neurones, response strength did not depend on dose or on which substance was used, DSIP among them.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
No significant changeDependence of neuronal response intensity on concentration and substance type
Study
molluscn: not reported in source
Isolated molluscan neurones
Outcome group
Brain and neuronal activity · Nervous system and cognition
Source sentences
Summary
The intensities of neuronal reactions didn't depend in contact period on the concentration and on the type of substance.
1 context sentence(design, population, supporting numbers)
Summary · context
The isolated neurones were placed into the special chamber.
In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).
Report a problemFND-1288198602

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Versions 4 to 12Current
28 Oct 2026, 02:02 UTC
The same notice was added 9 times, first on 21 Oct 2026, 15:59 UTC. The status did not change between them.
Study results updated
Version 3
21 Oct 2026, 12:50 UTC
Study data updated · source update from Europe PMC
Version 2
12 Oct 2026, 17:28 UTC
Study results updated
Version 1
9 Oct 2026, 03:04 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.