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Study · Not a test of the peptide alone · 2003

3 results

Growth-hormone response to combined stimulation with GHRH plus GH-releasing peptide-6 in obese patients with polycystic ovary syndrome before and after short-term fasting.

Micić D, Sumarac-Dumanović M, Macut Dj, Kendereski A, Zoric S, Popović V, Cvijović G, Dieguez C, Casanueva FF

Journal of endocrinological investigation1 Apr 2003Cited by 3 (Europe PMC)

PMID12841541 (opens in a new tab)DOI10.1007/bf03345181 (opens in a new tab)PepBankPUB-12841541
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHRP-6.

  1. 01HumanNot a test of GHRP-6 aloneNon-randomized trialEfficacy outcome

    In obese women, those with PCOS had a significantly greater GH peak after combined GHRH and GHRP‑6 before fasting than obese controls.

    In plain wordsIn obese women, those with PCOS had a larger growth hormone peak after GHRH plus GHRP‑6 than obese women without PCOS.

    Peptide
    GHRP-6
    Outcome
    IncreaseGH peak after GHRH+GHRP-6 before fasting
    Study

    n = 21

    Comparator
    Obese control women
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    Obese PCOS patients had significantly greater GH peak after GHRH+GHRP-6 before fasting.
    2 context sentences
    Summary · context
    Twelve obese PCOS women and nine obese control women participated in 3-day fasting.
    Summary · context
    GH response, IGF-I, insulin and leptin were measured after GHRH+ GHRP-6, before and after short-term fasting.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  2. 02HumanNot a test of GHRP-6 aloneNon-randomized trialEfficacy outcome

    In obese women with and without PCOS, the GH response to combined GHRH and GHRP‑6 was enhanced after short-term fasting.

    In plain wordsIn obese women, the growth hormone response to GHRH plus GHRP‑6 was larger after a short fast.

    Peptide
    GHRP-6
    Outcome
    IncreaseGH response to GHRH+GHRP-6 after fasting
    Study

    n = 21

    Comparator
    Before fasting
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    Enhanced response to GH stimulation was found after fasting
    2 context sentences
    Summary · context
    Twelve obese PCOS women and nine obese control women participated in 3-day fasting.
    Summary · context
    GH response, IGF-I, insulin and leptin were measured after GHRH+ GHRP-6, before and after short-term fasting.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  3. 03HumanNot a test of GHRP-6 aloneNon-randomized trialEfficacy outcome

    After fasting, the GH response to combined GHRH and GHRP‑6 did not differ substantially between obese women with PCOS and obese controls.

    In plain wordsAfter a short fast, the growth hormone response to GHRH plus GHRP‑6 was similar in obese women with and without PCOS.

    Peptide
    GHRP-6
    Outcome
    No significant changeGH response after fasting, PCOS versus controls
    Study

    n = 21

    Comparator
    Obese control women
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    Enhanced response to GH stimulation was found after fasting without substantial differences between obese PCOS and obese controls.
    2 context sentences
    Summary · context
    Twelve obese PCOS women and nine obese control women participated in 3-day fasting.
    Summary · context
    GH response, IGF-I, insulin and leptin were measured after GHRH+ GHRP-6, before and after short-term fasting.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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