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Study · Measured the body's own peptide · 2003

1 result

Plasma oxytocin in response to pharmaco-challenge to D-fenfluramine and placebo in healthy men.

Lee R, Garcia F, van de Kar LD, Hauger RD, Coccaro EF

Psychiatry research1 May 2003Cited by 24 (Europe PMC)

PMID12798977 (opens in a new tab)DOI10.1016/s0165-1781(03)00070-2 (opens in a new tab)PepBankPUB-12798977
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelNon-randomized trialOther

    In fourteen healthy men, a D-fenfluramine challenge was associated with an increase in plasma oxytocin compared with placebo.

    In plain wordsIn fourteen healthy men, a serotonin-releasing drug raised the body's own oxytocin level in blood compared with placebo.

    Peptide
    Oxytocin
    Outcome
    IncreasePlasma oxytocin after D-fenfluramine challenge
    Study

    n = 14

    Comparator
    Placebo
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones

    Source sentences

    Summary
    D-FEN was associated with an increase in both oxytocin
    2 context sentences
    Summary · context
    Fourteen male healthy subjects underwent a placebo challenge and a D-fenfluramine (D-FEN) (0.5 mg/kg) challenge on different days.
    Summary · context
    Serial plasma oxytocin and prolactin levels were measured on each challenge day.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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