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Study · Measured the body's own peptide · 2003

1 result

Facilitative role of prolactin-releasing peptide neurons in oxytocin cell activation after conditioned-fear stimuli.

Zhu LL, Onaka T

Neuroscience1 Jan 2003Cited by 42 (Europe PMC)

PMID12732249 (opens in a new tab)DOI10.1016/s0306-4522(03)00059-9 (opens in a new tab)PepBankPUB-12732249
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In rats given conditioned-fear stimuli, an intracerebroventricular anti-PrRP antibody impaired the release of oxytocin.

    In plain wordsIn rats, blocking a brain signal called PrRP reduced the release of the body's own oxytocin after fear stimuli.

    Peptide
    Oxytocin
    Outcome
    DecreaseOxytocin release after anti-PrRP antibody
    Study

    ratn: not reported in source

    rats after conditioned-fear stimuli
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones

    Source sentences

    Summary
    An i.c.v. injection of a mouse monoclonal anti-PrRP antibody impaired release of oxytocin but not of adrenocorticotrophic hormone or prolactin and did not significantly change freezing behavior in response to conditioned-fear stimuli.
    1 context sentence
    Summary · context
    To test this hypothesis, we first examined expression of Fos protein, an immediate early gene product, in the PrRP neurons in the medulla oblongata after conditioned-fear stimuli.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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