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Study · Measured the body's own peptide · 2003

2 results

Expression and splicing of the insulin-like growth factor gene in rodent muscle is associated with muscle satellite (stem) cell activation following local tissue damage.

Hill M, Goldspink G

The Journal of physiology11 Apr 2003Cited by 199 (Europe PMC)

PMID12692175 (opens in a new tab)DOI10.1113/jphysiol.2002.035832 (opens in a new tab)PepBankPUB-12692175
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In rats with mechanical muscle damage, MGF mRNA was rapidly expressed and then declined within a few days.

    In plain wordsIn rats with muscle damage from stretch and stimulation, the body's own MGF rose quickly and then fell within days.

    Peptide
    MGF / PEG-MGF
    Outcome
    MixedMGF mRNA time course after mechanical muscle damage
    Study

    ratn: not reported in source

    Electrical stimulation of stretched tibialis anterior
    Outcome group
    Muscle injury and repair · Musculoskeletal

    Source sentences

    Summary
    It was found that the autocrine splice variant mechano growth factor (MGF) was rapidly expressed and then declined within a few days following both types of damage.
    1 context sentence
    Summary · context
    Using real-time RT-PCR with specific primers, the mRNA transcripts in rat tibialis anterior muscles were measured at different time intervals following either mechanical damage imposed by electrical stimulation of the stretched muscle or damage caused by injection with bupivacaine.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In rats with bupivacaine-induced muscle damage, MGF mRNA was rapidly expressed and then declined within a few days.

    In plain wordsIn rats with muscle damage from a bupivacaine injection, the body's own MGF rose quickly and then fell within days.

    Peptide
    MGF / PEG-MGF
    Outcome
    MixedMGF mRNA time course after bupivacaine muscle damage
    Study

    ratn: not reported in source

    Bupivacaine injection into tibialis anterior
    Outcome group
    Muscle injury and repair · Musculoskeletal

    Source sentences

    Summary
    It was found that the autocrine splice variant mechano growth factor (MGF) was rapidly expressed and then declined within a few days following both types of damage.
    1 context sentence
    Summary · context
    Using real-time RT-PCR with specific primers, the mRNA transcripts in rat tibialis anterior muscles were measured at different time intervals following either mechanical damage imposed by electrical stimulation of the stretched muscle or damage caused by injection with bupivacaine.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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