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Study · Ex vivo tissue · sea bream (sparus aurata) · 2003

2 results

The regulatory action of estrogen and vasoactive intestinal peptide on prolactin secretion in sea bream (Sparus aurata, L.).

Brinca L, Fuentes J, Power DM

General and comparative endocrinology1 Apr 2003Cited by 17 (Europe PMC)

PMID12679088 (opens in a new tab)DOI10.1016/s0016-6480(02)00628-7 (opens in a new tab)PepBankPUB-12679088
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueEfficacy outcome

    In pituitary cultures from estradiol-primed sea bream, VIP caused a dose-dependent inhibition of prolactin secretion.

    In plain wordsIn lab cultures of fish pituitary glands, VIP lowered prolactin release in a dose-dependent way after estradiol priming.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    DecreaseProlactin secretion in E2-primed pituitaries
    Study

    sea bream (Sparus aurata)n: not reported in source

    pituitary cultures
    Comparator
    No VIP
    Outcome group
    Pituitary hormones · Endocrine and hormones
    Studied dose
    0-200 nM · 18 hAs given in this study (sea bream (Sparus aurata)).

    Source sentences

    Summary
    In E(2) primed fish VIP caused a dose-dependent inhibition of PRL secretion in vitro.
    2 context sentences
    Summary · context
    The effect of estradiol-17beta (E(2)) implants on the in vitro secretion of prolactin (PRL) and its modulation by vasoactive intestinal peptide (VIP) in a marine teleost, sea bream (Sparus aurata L.), was determined.
    Summary · context
    Fish were sacrificed after 7 days treatment and in vitro pituitary cultures in Ringer bicarbonate supplemented with increasing doses (0-200 nM) of VIP were carried out for 18 h.
  2. 02LabEx vivo tissueEfficacy outcome

    In pituitary cultures from control sea bream, VIP had no detectable effect on prolactin secretion.

    In plain wordsIn lab cultures of control fish pituitary glands, VIP did not change prolactin release.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    No significant changeProlactin secretion in control pituitaries
    Study

    sea bream (Sparus aurata)n: not reported in source

    pituitary cultures
    Comparator
    No VIP
    Outcome group
    Pituitary hormones · Endocrine and hormones
    Studied dose
    0-200 nM · 18 hAs given in this study (sea bream (Sparus aurata)).

    Source sentences

    Summary
    VIP had no detectable effect on the secretion of PRL from control pituitaries.
    2 context sentences
    Summary · context
    The effect of estradiol-17beta (E(2)) implants on the in vitro secretion of prolactin (PRL) and its modulation by vasoactive intestinal peptide (VIP) in a marine teleost, sea bream (Sparus aurata L.), was determined.
    Summary · context
    Fish were sacrificed after 7 days treatment and in vitro pituitary cultures in Ringer bicarbonate supplemented with increasing doses (0-200 nM) of VIP were carried out for 18 h.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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