In immunosuppressed mdx mice, human synovial membrane stem cells administered into dystrophic muscle rescued the expression of mouse mechano growth factor.
In plain wordsIn mice with muscular dystrophy, implanted human stem cells restored the mouse's own MGF expression in muscle.
- Peptide
- MGF / PEG-MGF
- Outcome
- IncreaseMouse MGF expression after stem cell implant in mdx muscle
- Study
mousen: not reported in source
mdx mouse model of Duchenne muscular dystrophy- Outcome group
- Muscle injury and repair · Musculoskeletal
Source sentences
When administered into dystrophic muscles of immunosuppressed mdx mice, hSM-MSCs restored sarcolemmal expression of dystrophin, reduced central nucleation, and rescued the expression of mouse mechano growth factor.
1 context sentence(design, population, supporting numbers)
In the present study, we have characterized their myogenic differentiation in a nude mouse model of skeletal muscle regeneration and provide proof of principle of their potential use for muscle repair in the mdx mouse model of Duchenne muscular dystrophy.
This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.