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Study · Not a test of the peptide alone · 2003

1 result

Intracellular mechanisms involved in leptin regulation of sympathetic outflow.

Rahmouni K, Haynes WG, Morgan DA, Mark AL

Hypertension (Dallas, Tex. : 1979)16 Dec 2002Cited by 89 (Europe PMC)

PMID12623993 (opens in a new tab)DOI10.1161/01.hyp.0000048342.54392.40 (opens in a new tab)PepBankPUB-12623993
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, Melanotan II was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Melanotan II.

  1. 01AnimalNot a test of Melanotan II aloneAnimal study (in vivo)Mechanism

    In mice, PI3K inhibitors did not change the renal sympathetic nerve response to MTII.

    In plain wordsIn mice, drugs that block PI3K did not change how MTII affected kidney nerve activity.

    Peptide
    Melanotan II
    Outcome
    No significant changeRSNA response to MTII with PI3K inhibitors
    Study

    mousen: not reported in source

    Outcome group
    Brain and neuronal activity · Cardiovascular

    Source sentences

    Summary
    In contrast, PI3K inhibitors did not affect the RSNA response to MTII (melanocortin-3/4 receptor agonist).
    1 context sentence
    Summary · context
    We evaluated renal sympathetic nerve activity (RSNA) and feeding responses of C57BL/6J mice to intracerebroventricular (ICV) administration of leptin in the presence or absence of selective inhibitors of PI3K (LY294002 or wortmannin).

    In this study, Melanotan II was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Melanotan II.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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