Skip to content

Study · Animal study (in vivo) · rat · 2003

1 result

Differential sensitivity to central leptin and insulin in male and female rats.

Clegg DJ, Riedy CA, Smith KA, Benoit SC, Woods SC

Diabetes1 Mar 2003Cited by 256 (Europe PMC)

PMID12606509 (opens in a new tab)DOI10.2337/diabetes.52.3.682 (opens in a new tab)PepBankPUB-12606509
Source linkPubMedAsk about this study
Jump to 1 result

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In male and female rats, the melanocortin agonist MTII showed no sex difference in sensitivity.

    In plain wordsIn rats, males and females were equally sensitive to MTII.

    Peptide
    Melanotan II
    Outcome
    No significant changeSex difference in sensitivity to MTII
    Study

    ratn: not reported in source

    Comparator
    Male versus female rats
    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    0.01, 0.1, 0.3, and 1.0 nmol/2 microlAs given in this study (rat).

    Source sentences

    Summary
    However, we found no sex differences in sensitivity to the melanocortin agonist MTII (0.01, 0.1, 0.3, and 1.0 nmol/2 microl).
    1 context sentence
    Summary · context
    We now report that the brains of male and female rats are differentially sensitive to the catabolic actions of small doses of these two hormones.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.