In porcine embryonic myogenic cells, recombinant porcine IGFBP-3 suppressed Long-R3-IGF-I-stimulated proliferation, which indicates IGF-independent activity of IGFBP-3.
In plain wordsIn cells, the binding protein IGFBP-3 reduced growth of muscle cells that Long-R3-IGF-I had stimulated. The agent tested was IGFBP-3.
- Peptide
- IGF-1 LR3
- Outcome
- DecreaseLong-R3-IGF-I-stimulated proliferation with rpIGFBP-3
- Study
pign: not reported in source
Porcine embryonic myogenic cell (PEMC) cultures- Outcome group
- Cell proliferation and differentiation · Musculoskeletal
Source sentences
rpIGFBP-3 also suppressed Long-R3-IGF-I-stimulated proliferation of PEMC, indicating that rpIGFBP-3 possesses IGF-independent activity in this cell system.
In this study, IGF-1 LR3 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking IGF-1 LR3.