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Study · In vitro (cells) · 2002

3 results

[Ani immunomodulator Hepon inhibits hepatitis C virus replication in human cell cultures in vitro].

Ataullakhanov RI, Holms RD, Katlinskiĭ AV, Deriabin PG, Narovlianskiĭ AN, Mezentseva MV, Ershov FI

Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]1 Jan 2002Cited by 1 (Europe PMC)

PMID12515090 (opens in a new tab)PepBankPUB-12515090
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    In human SW-13 cell culture, Hepon protected cells from hepatitis C virus cytopathogenic effects.

    In plain wordsIn cells, Hepon protected against damage from hepatitis C virus.

    Peptide
    Gepon
    Outcome
    IncreaseProtection from viral cytopathogenic effects
    Study

    humann: not reported in source

    Hepatitis C virus-infected SW-13 cells
    Outcome group
    Antiviral activity · Infection
    Studied dose
    Dose not stated

    Source sentences

    Summary
    "Hepon" presence protected human cells SW-13 from cytopathogenic effect of hepatitis C virus.
    1 context sentence
    Summary · context
    Antiviral activity of immunomodulator "Hepon" was evaluated in human cells culture infected with hepatitis C virus.
  2. 02LabIn vitro (cells)Activity measurement

    In human cell culture, Hepon showed its maximum antiviral effect at 1 mcg/mL.

    In plain wordsIn cells, Hepon showed its greatest antiviral effect at 1 mcg/mL.

    Peptide
    Gepon
    Outcome
    Not applicableMaximum antiviral effect concentration
    Study

    humann: not reported in source

    Hepatitis C virus-infected SW-13 cells
    Outcome group
    Antiviral activity · Infection
    Studied dose
    1 mcg/mLAs given in this study (human).

    Source sentences

    Summary
    Maximum antiviral effect was demonstrated by "Hepon" at concentration 1 mcg/mL.
    1 context sentence
    Summary · context
    Antiviral activity of immunomodulator "Hepon" was evaluated in human cells culture infected with hepatitis C virus.
  3. 03LabIn vitro (cells)Activity measurement

    In human SW-13 cell culture, Hepon was less potent than reaferon at protecting cell vitality.

    In plain wordsIn cells, Hepon protected cell survival less strongly than reaferon.

    Peptide
    Gepon
    Outcome
    DecreaseCell vitality protection versus reaferon
    Study

    humann: not reported in source

    Hepatitis C virus-infected SW-13 cells
    Comparator
    Reaferon (interferon alfa-2a)
    Outcome group
    Antiviral activity · Infection
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Control antiviral agent reaferon (interferon alfa-2a) was more potent as vitality protecting agent in the case of SW-13 human cells culture.
    1 context sentence
    Summary · context
    Antiviral activity of immunomodulator "Hepon" was evaluated in human cells culture infected with hepatitis C virus.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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