In recipient mice, leuprolide treatment did not influence human spermatogonial stem cell colonization.
In plain wordsIn mice receiving human testis cells, leuprolide did not change stem cell colonization compared with recipients without leuprolide.
- Peptide
- Leuprolide
- Outcome
- No significant changeHuman stem cell colonization
- Study
mousen: not reported in source
Immunodeficient mice receiving human testis cells- Comparator
- Recipients without leuprolide treatment
- Outcome group
- Sex hormones and fertility · Reproductive and sexual health
- Studied dose
- Dose not stated
Source sentences
In this initial study, human stem cell colonization was not influenced by cryopreservation of donor cells, donor cell concentration, or leuprolide treatment of recipient mice.
2 context sentences(design, population, supporting numbers)
Transplantation of human testis cells into the seminiferous tubules of immunodeficient mice.
Also analyzed: cryopreservation of donor cells, donor cell concentrations, and leuprolide treatment of recipients.