In patients with refractory peptic ulcers, intranasal Semax with traditional drugs gave ulcer healing on day 14 in 89.5% of patients versus 30.8% in the control group.
In plain wordsIn patients with hard-to-treat stomach ulcers, more healed by day 14 with nose-drop Semax than in the control group.
- Peptide
- Semax
- Outcome
- IncreaseUlcer healing on day 14
- Study
n: not reported in source
- Comparator
- Control group
- Outcome group
- Gastrointestinal protection · Gastrointestinal
- Studied dose
- 1% solution, 2-4 drops 3 times a day · intranasal · 10 daysAs given in this study (human).
Measurements
- Ulcer healing on day 14
- 89.5%
- Semax
- Ulcer healing on day 14
- 30.8%
- control group
Source sentences
On day 14 of treatment ulcer healing was observed in 89.5% patients receiving intranasal Semax (1% solution, 2-4 drops 3 times a day for 10 days) vs. 30.8% in the control group.
1 context sentence(design, population, supporting numbers)
Experiments used is combination with traditional preparations (omeprasole, de-nol, and solcoseril), Semax peptide (Met-Glu-His-Phe-Pro-Gly-Pro) possessing nootropic and neuroprotective activity significantly promoted ulcer healing in patients with refractory peptic ulcers.