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Study · Other design · 2002

3 results

Pineal-regulating tetrapeptide epitalon improves eye retina condition in retinitis pigmentosa.

Khavinson V, Razumovsky M, Trofimova S, Grigorian R, Razumovskaya A

Neuro endocrinology letters1 Aug 2002Cited by 8 (Europe PMC)

PMID12195242 (opens in a new tab)PepBankPUB-12195242
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 1 result from people.

  1. 01HumanOther designEfficacy outcome

    In patients with degenerative retinal lesions, Epitalon therapy resulted in a positive clinical effect in 90% of the cases.

    In plain wordsIn patients with degenerative retinal lesions, 90% had a positive clinical effect with Epitalon therapy; the study had no stated comparison group.

    Peptide
    Epitalon
    Outcome
    Not applicablePositive clinical effect in patients with degenerative retinal lesions
    Study

    n: not reported in source

    Outcome group
    Vision and retina · Eye
    Studied dose
    Dose not stated

    Measurements

    Patients with positive clinical effect
    90%
    Epitalon therapy

    Source sentences

    Summary
    Epitalon therapy in patients with degenerative retinal lesions results in a positive clinical effect in 90% of the cases.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In Campbell rats with congenital pigmented retinal degeneration, Epitalon intensified the bioelectric and functional activity of the retina.

    In plain wordsIn rats with inherited retinal degeneration, Epitalon increased the electrical and functional activity of the retina.

    Peptide
    Epitalon
    Outcome
    IncreaseBioelectric and functional activity of the retina
    Study

    Rat (Campbell)n: not reported in source

    Congenital pigmented retinal degeneration
    Outcome group
    Vision and retina · Eye
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The application of Epitalon in Campbell rats is found to intensify the bioelectric and functional activity of the retina due to the preservation of its morphological structure.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In Campbell rats with congenital pigmented retinal degeneration, Epitalon was associated with preservation of the morphological structure of the retina.

    In plain wordsIn rats with inherited retinal degeneration, Epitalon went with better preservation of the retina structure.

    Peptide
    Epitalon
    Outcome
    IncreasePreservation of retinal morphological structure
    Study

    Rat (Campbell)n: not reported in source

    Congenital pigmented retinal degeneration
    Outcome group
    Vision and retina · Eye
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The application of Epitalon in Campbell rats is found to intensify the bioelectric and functional activity of the retina due to the preservation of its morphological structure.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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