[Pharmacological efficacy of delta sleep-inducing peptide in experimental acute pancreatitis].

Bondarenko TI, Kalmykova IuA, Shustanova TA, Mikhaleva II

Eksperimental'naia i klinicheskaia farmakologiia1 Mar 2002

PMID12109293PepBankPUB-12109293

Summary

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Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study7

7 results from studies that gave the peptide. No result from this study comes from people.

01AnimalAnimal study (in vivo)Efficacy outcome
In rats with experimental acute pancreatitis, preliminary triple intraperitoneal DSIP stabilized lipid peroxidation.
In plain wordsIn rats with acute pancreatitis, DSIP given beforehand kept lipid peroxidation stable.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
DecreaseLipid peroxidation
Study
ratn: not reported in source
experimental acute pancreatitis
Outcome group
Inflammation markers · Whole body
Studied dose
12 micrograms/100 g body weight · intraperitonealAs given in this study (rat).
Source sentences
Summary
Preliminary triple intraperitoneal administration of a delta-sleep-inducing peptide (DSIP) in a dose of 12 micrograms/100 g body weight to the test rats with EOP stabilized LPO, improved the erythrocyte membrane structure, reduced the MDA level in tissues and blood serum, increased ORE, reduced the…
Report a problemFND-1210929301
02AnimalAnimal study (in vivo)Efficacy outcome
In rats with experimental acute pancreatitis, preliminary triple intraperitoneal DSIP improved erythrocyte membrane structure.
In plain wordsIn rats with acute pancreatitis, DSIP given beforehand improved the structure of red blood cell membranes.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
IncreaseErythrocyte membrane structure
Study
ratn: not reported in source
experimental acute pancreatitis
Outcome group
Inflammation markers · Whole body
Studied dose
12 micrograms/100 g body weight · intraperitonealAs given in this study (rat).
Source sentences
Summary
Preliminary triple intraperitoneal administration of a delta-sleep-inducing peptide (DSIP) in a dose of 12 micrograms/100 g body weight to the test rats with EOP stabilized LPO, improved the erythrocyte membrane structure, reduced the MDA level in tissues and blood serum, increased ORE, reduced the…
Report a problemFND-1210929302
03AnimalAnimal study (in vivo)Efficacy outcome
In rats with experimental acute pancreatitis, preliminary triple intraperitoneal DSIP reduced MDA levels in tissues and blood serum.
In plain wordsIn rats with acute pancreatitis, DSIP given beforehand lowered a marker of fat damage (MDA) in tissues and blood.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
DecreaseMalonic dialdehyde (MDA) in tissues and blood serum
Study
ratn: not reported in source
experimental acute pancreatitis
Outcome group
Inflammation markers · Whole body
Studied dose
12 micrograms/100 g body weight · intraperitonealAs given in this study (rat).
Source sentences
Summary
Preliminary triple intraperitoneal administration of a delta-sleep-inducing peptide (DSIP) in a dose of 12 micrograms/100 g body weight to the test rats with EOP stabilized LPO, improved the erythrocyte membrane structure, reduced the MDA level in tissues and blood serum, increased ORE, reduced the…
Report a problemFND-1210929303
04AnimalAnimal study (in vivo)Efficacy outcome
In rats with experimental acute pancreatitis, preliminary triple intraperitoneal DSIP increased the osmotic resistance of erythrocytes.
In plain wordsIn rats with acute pancreatitis, DSIP given beforehand made red blood cells more resistant to osmotic stress.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
IncreaseOsmotic resistance of erythrocytes (ORE)
Study
ratn: not reported in source
experimental acute pancreatitis
Outcome group
Inflammation markers · Whole body
Studied dose
12 micrograms/100 g body weight · intraperitonealAs given in this study (rat).
Source sentences
Summary
Preliminary triple intraperitoneal administration of a delta-sleep-inducing peptide (DSIP) in a dose of 12 micrograms/100 g body weight to the test rats with EOP stabilized LPO, improved the erythrocyte membrane structure, reduced the MDA level in tissues and blood serum, increased ORE, reduced the…
Report a problemFND-1210929304
05AnimalAnimal study (in vivo)Efficacy outcome
In rats with experimental acute pancreatitis, preliminary triple intraperitoneal DSIP reduced extracorpuscular hemoglobin in the blood.
In plain wordsIn rats with acute pancreatitis, DSIP given beforehand lowered free hemoglobin in the blood.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
DecreaseExtracorpuscular hemoglobin (ECH) in blood
Study
ratn: not reported in source
experimental acute pancreatitis
Outcome group
Inflammation markers · Whole body
Studied dose
12 micrograms/100 g body weight · intraperitonealAs given in this study (rat).
Source sentences
Summary
Preliminary triple intraperitoneal administration of a delta-sleep-inducing peptide (DSIP) in a dose of 12 micrograms/100 g body weight to the test rats with EOP stabilized LPO, improved the erythrocyte membrane structure, reduced the MDA level in tissues and blood serum, increased ORE, reduced the…
Report a problemFND-1210929305
06AnimalAnimal study (in vivo)Efficacy outcome
In rats with experimental acute pancreatitis, preliminary triple intraperitoneal DSIP reduced medium-molecular-weight molecules in the blood.
In plain wordsIn rats with acute pancreatitis, DSIP given beforehand lowered medium-sized molecules in the blood.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
DecreaseMedium-molecular-weight molecules (MWM) in blood
Study
ratn: not reported in source
experimental acute pancreatitis
Outcome group
Inflammation markers · Whole body
Studied dose
12 micrograms/100 g body weight · intraperitonealAs given in this study (rat).
Source sentences
Summary
Preliminary triple intraperitoneal administration of a delta-sleep-inducing peptide (DSIP) in a dose of 12 micrograms/100 g body weight to the test rats with EOP stabilized LPO, improved the erythrocyte membrane structure, reduced the MDA level in tissues and blood serum, increased ORE, reduced the…
Report a problemFND-1210929306
07AnimalAnimal study (in vivo)Efficacy outcome
In rats with experimental acute pancreatitis, preliminary triple intraperitoneal DSIP decreased the protein autolysis rate in tissues.
In plain wordsIn rats with acute pancreatitis, DSIP given beforehand slowed protein breakdown in tissues.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
DecreaseProtein autolysis rate in tissues
Study
ratn: not reported in source
experimental acute pancreatitis
Outcome group
Inflammation markers · Whole body
Studied dose
12 micrograms/100 g body weight · intraperitonealAs given in this study (rat).
Source sentences
Summary
Preliminary triple intraperitoneal administration of a delta-sleep-inducing peptide (DSIP) in a dose of 12 micrograms/100 g body weight to the test rats with EOP stabilized LPO, improved the erythrocyte membrane structure, reduced the MDA level in tissues and blood serum, increased ORE, reduced the…
Report a problemFND-1210929307

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
12 Oct 2026, 17:28 UTC
Study results updated
Version 1
9 Oct 2026, 03:04 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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MeSH terms

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