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Study · Animal study (in vivo) · rat · 2002

2 results

Changes in glucocorticoid and mineralocorticoid receptors of liver and kidney cytosols after pathologic stress and its regulation in rats.

Liu DH, Su YP, Zhang W, Lu SF, Ran XZ, Gao JS, Cheng TM

Critical care medicine1 Mar 2002Cited by 14 (Europe PMC)

PMID11990926 (opens in a new tab)DOI10.1097/00003246-200203000-00022 (opens in a new tab)PepBankPUB-11990926
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats with heavy-degree scald, KPV peptide injections might prevent the reduction in glucocorticoid receptor binding capacity in hepatic cytosol.

    In plain wordsIn rats with a severe scald, KPV injections might stop the drop in liver glucocorticoid receptor binding.

    Peptide
    KPV
    Outcome
    IncreaseGlucocorticoid receptor binding capacity in hepatic cytosol
    Study

    ratn: not reported in source

    Wistar rats with heavy-degree immersion scald
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    and KPV peptide (Ac-D-Lys-L-Pro-D-Val) might prevent a reduction in the binding capacity of glucocorticoid receptor in hepatic cytosols and mineralocorticoid receptor in kidney cytosols in rats with heavy-degree scald in vivo.
    1 context sentence
    Summary · context
    Male Wistar rats (weight range, 180-200 g).
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats with heavy-degree scald, KPV peptide injections might prevent the reduction in mineralocorticoid receptor binding capacity in kidney cytosol.

    In plain wordsIn rats with a severe scald, KPV injections might stop the drop in kidney mineralocorticoid receptor binding.

    Peptide
    KPV
    Outcome
    IncreaseMineralocorticoid receptor binding capacity in kidney cytosol
    Study

    ratn: not reported in source

    Wistar rats with heavy-degree immersion scald
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    and KPV peptide (Ac-D-Lys-L-Pro-D-Val) might prevent a reduction in the binding capacity of glucocorticoid receptor in hepatic cytosols and mineralocorticoid receptor in kidney cytosols in rats with heavy-degree scald in vivo.
    1 context sentence
    Summary · context
    Male Wistar rats (weight range, 180-200 g).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:56 UTC

    First added · source update from Europe PMC

Subjects

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