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Study · Measured the body's own peptide · 2002

2 results

Up-regulation of vasopressin and angiotensin II receptors in the thalamus and brainstem of inbred polydipsic mice.

Tribollet E, Ueta Y, Heitz F, Marguerat A, Koizumi K, Yamashita H

Neuroendocrinology1 Feb 2002Cited by 14 (Europe PMC)

PMID11867939 (opens in a new tab)DOI10.1159/000048227 (opens in a new tab)PepBankPUB-11867939
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    Distribution and amount of oxytocin receptor binding were similar in polydipsic and control mice.

    In plain wordsIn mice, the body's own oxytocin receptors looked similar in mice with excess thirst and in control mice.

    Peptide
    Oxytocin
    Outcome
    No significant changeOxytocin receptor binding, polydipsic versus control mice
    Study

    mousen: not reported in source

    Polydipsic STR/N mice versus control ICR mice, receptor autoradiography
    Comparator
    Control non-polydipsic ICR mice
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    The distribution and amount of OT receptor binding were similar in the polydipsic and control mice.
    1 context sentence
    Summary · context
    Vasopressin (AVP), angiotensin II (Ang II) and oxytocin (OT) receptors were mapped in the brain of inbred polydipsic mice of the STR/N strain by quantitative in vitro autoradiography and receptor binding levels, compared with those found in control non-polydipsic mice of the ICR strain.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Mechanism

    Oxytocin receptor labelling in the hypothalamic ventromedial nucleus was less intense in males than in females of both strains.

    In plain wordsIn mice, labelling of the body's own oxytocin receptors in one brain area was less intense in males than in females.

    Peptide
    Oxytocin
    Outcome
    DecreaseOxytocin receptor binding in hypothalamic ventromedial nucleus, males versus females
    Study

    mousen: not reported in source

    Polydipsic STR/N mice versus control ICR mice, receptor autoradiography
    Comparator
    Female mice
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    A sex-related difference was seen only for OT receptor binding in the hypothalamic ventromedial nucleus, where labelling was less intense in males than in females of both strains.
    1 context sentence
    Summary · context
    Vasopressin (AVP), angiotensin II (Ang II) and oxytocin (OT) receptors were mapped in the brain of inbred polydipsic mice of the STR/N strain by quantitative in vitro autoradiography and receptor binding levels, compared with those found in control non-polydipsic mice of the ICR strain.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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