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Study · Not a test of the peptide alone · 2002

3 results

A novel in vivo rabbit model of hypercatabolic critical illness reveals a biphasic neuroendocrine stress response.

Weekers F, Van Herck E, Coopmans W, Michalaki M, Bowers CY, Veldhuis JD, Van den Berghe G

Endocrinology1 Mar 2002Cited by 57 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHRP-2.

  1. 01AnimalNot a test of GHRP-2 aloneAnimal study (in vivo)Mechanism

    In rabbits with burn-induced prolonged critical illness, GH responses to a GHRP‑2 + TRH bolus were higher than in controls on day 1 and rose further on day 8.

    In plain wordsIn rabbits with prolonged critical illness, growth hormone responses to a GHRP‑2 and TRH injection were higher than in controls.

    Peptide
    GHRP-2
    Outcome
    IncreaseGH response to GHRP-2 + TRH bolus
    Study

    rabbitn: not reported in source

    Burn-induced prolonged critical illness in New Zealand White rabbits
    Comparator
    Healthy control rabbits
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    GH responses to GHRP-2 + TRH were elevated on d 1 and increased further on d 8 in the critically ill animals.
    2 context sentences
    Summary · context
    Seven days after arterial and venous cannulae placement, male New Zealand White rabbits were randomly allocated to a control or a critically ill group.
    Summary · context
    To induce prolonged critical illness, a template controlled 15% deep dermal burn injury was imposed under combined general and regional (paravertebral) anesthesia.

    In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-2.

  2. 02AnimalNot a test of GHRP-2 aloneAnimal study (in vivo)Mechanism

    In rabbits with burn-induced prolonged critical illness, TSH responses to GHRP‑2 and TRH were increased only on day 1.

    In plain wordsIn rabbits with critical illness, thyroid-stimulating hormone responses to a GHRP‑2 and TRH injection were higher only on day 1.

    Peptide
    GHRP-2
    Outcome
    IncreaseTSH response to GHRP-2 + TRH bolus
    Study

    rabbitn: not reported in source

    Burn-induced prolonged critical illness in New Zealand White rabbits
    Comparator
    Healthy control rabbits
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    TSH and PRL responses to GHRP-2 and TRH were increased only on d 1.
    2 context sentences
    Summary · context
    Seven days after arterial and venous cannulae placement, male New Zealand White rabbits were randomly allocated to a control or a critically ill group.
    Summary · context
    To induce prolonged critical illness, a template controlled 15% deep dermal burn injury was imposed under combined general and regional (paravertebral) anesthesia.

    In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-2.

  3. 03AnimalNot a test of GHRP-2 aloneAnimal study (in vivo)Mechanism

    In rabbits with burn-induced prolonged critical illness, PRL responses to GHRP‑2 and TRH were increased only on day 1.

    In plain wordsIn rabbits with critical illness, prolactin responses to a GHRP‑2 and TRH injection were higher only on day 1.

    Peptide
    GHRP-2
    Outcome
    IncreasePRL response to GHRP-2 + TRH bolus
    Study

    rabbitn: not reported in source

    Burn-induced prolonged critical illness in New Zealand White rabbits
    Comparator
    Healthy control rabbits
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    TSH and PRL responses to GHRP-2 and TRH were increased only on d 1.
    2 context sentences
    Summary · context
    Seven days after arterial and venous cannulae placement, male New Zealand White rabbits were randomly allocated to a control or a critically ill group.
    Summary · context
    To induce prolonged critical illness, a template controlled 15% deep dermal burn injury was imposed under combined general and regional (paravertebral) anesthesia.

    In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-2.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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