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Study · In vitro (cells) · mink · 2002

1 result

Insulin-like growth factor binding protein-2 mediates the inhibition of DNA synthesis by transforming growth factor-beta in mink lung epithelial cells.

Dong F, Wu HB, Hong J, Rechler MM

Journal of cellular physiology1 Jan 2002Cited by 11 (Europe PMC)

PMID11807812 (opens in a new tab)DOI10.1002/jcp.10034 (opens in a new tab)PepBankPUB-11807812
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In mink lung epithelial cells, Long-R3-IGF-I did not decrease the inhibition of DNA synthesis by TGF-beta.

    In plain wordsIn lab tests on mink lung cells, Long-R3-IGF-I did not reduce the growth block caused by TGF-beta.

    Peptide
    IGF-1 LR3
    Outcome
    No significant changeReversal of TGF-beta inhibition of DNA synthesis
    Study

    minkn: not reported in source

    Mv1 mink lung epithelial cells (CCL64)
    Outcome group
    Receptor activity and mechanism · Respiratory
    Studied dose
    Dose not stated

    Source sentences

    Summary
    whereas Long-R3-IGF-I, an IGF-I analog with higher affinity for IGF-I receptors than for IGFBPs, did not decrease inhibition
    1 context sentence
    Summary · context
    The present study asks whether IGFBPs synthesized by CCL64 cells mediate growth inhibition by TGF-beta.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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