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Study · Animal study (in vivo) · rat · 2001

1 result

Structure-function studies of linear and cyclized peptide antagonists of the GnRH receptor.

Beckers T, Bernd M, Kutscher B, Kühne R, Hoffmann S, Reissmann T

Biochemical and biophysical research communications1 Dec 2001Cited by 32 (Europe PMC)

PMID11726197 (opens in a new tab)DOI10.1006/bbrc.2001.5939 (opens in a new tab)PepBankPUB-11726197
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In male rats, testosterone suppression below castration levels lasted 1 day with ganirelix versus 27 days with D-23487.

    In plain wordsIn rats, testosterone suppression below castration levels lasted 1 day with ganirelix versus 27 days with D-23487.

    Peptide
    Ganirelix
    Outcome
    DecreaseDuration of testosterone suppression below castration levels
    Study

    ratn: not reported in source

    Male rats
    Comparator
    D-23487
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    Dose not stated

    Measurements

    Suppression duration
    1 day
    Ganirelix
    Suppression duration
    27 days
    D-23487

    Source sentences

    Summary
    The duration of testosterone suppression below castration levels differed largely from 1 day for Ganirelix to 27 days for D-23487.
    1 context sentence
    Summary · context
    Finally, selected antagonists were tested for testosterone suppression in male rats.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 2

    27 Oct 2026, 16:35 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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