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Study · Ex vivo tissue · rat · 2001

4 results

Tissue-specific effects of peptides.

Khavinson VK

Bulletin of experimental biology and medicine1 Aug 2001Cited by 3 (Europe PMC)

PMID11713572 (opens in a new tab)DOI10.1023/a:1013058701974 (opens in a new tab)PepBankPUB-11713572
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueEfficacy outcome

    In organotypic cultures of rat tissue, Epithalon stimulated the growth of explants from subcortical structures of the brain.

    In plain wordsIn lab-grown rat tissue, epithalon stimulated the growth of explants from deeper brain structures.

    Peptide
    Epitalon
    Outcome
    IncreaseGrowth of explants from rat subcortical structures
    Study

    ratn: not reported in source

    Organotypic explant cultures
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Synthetic peptides (cytogens) Cortagen, Epithalon, Livagen, and Vilon stimulated the growth of explants from rat brain cortex, subcortical structures, liver, and thymus, respectively, in organotypic cultures.
    1 context sentence
    Summary · context
    These peptides produced tissue-specific effects: they stimulated the growth of explants from tissues, whose cytomedins (peptide complexes) were used for chemical synthesis.
  2. 02LabEx vivo tissueActivity measurement

    In rat organotypic cultures, Cortagen stimulated brain cortex explant growth.

    In plain wordsIn lab tests with rat tissue, Cortagen increased brain cortex explant growth.

    Peptide
    Cortagen (AEDP)
    Outcome
    IncreaseBrain cortex explant growth
    Study

    ratn: not reported in source

    Brain cortex explants in organotypic culture
    Outcome group
    Cell proliferation and differentiation · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Synthetic peptides (cytogens) Cortagen, Epithalon, Livagen, and Vilon stimulated the growth of explants from rat brain cortex, subcortical structures, liver, and thymus, respectively, in organotypic cultures.
  3. 03LabEx vivo tissueActivity measurement

    In rat organotypic cultures, Livagen stimulated liver explant growth.

    In plain wordsIn lab tests with rat tissues, Livagen stimulated liver explant growth.

    Peptide
    Livagen (KEDA)
    Outcome
    IncreaseLiver explant growth
    Study

    ratn: not reported in source

    Organotypic liver explant cultures
    Outcome group
    Cell proliferation and differentiation · Liver
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Synthetic peptides (cytogens) Cortagen, Epithalon, Livagen, and Vilon stimulated the growth of explants from rat brain cortex, subcortical structures, liver, and thymus, respectively, in organotypic cultures.
  4. 04LabEx vivo tissueActivity measurement

    In rat organotypic cultures, Vilon stimulated thymus explant growth.

    In plain wordsIn lab tests, Vilon stimulated growth of rat thymus tissue.

    Peptide
    Vilon (KE)
    Outcome
    IncreaseThymus explant growth
    Study

    ratn: not reported in source

    Thymus explants in organotypic culture
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Synthetic peptides (cytogens) Cortagen, Epithalon, Livagen, and Vilon stimulated the growth of explants from rat brain cortex, subcortical structures, liver, and thymus, respectively, in organotypic cultures.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Versions 6 to 12Current

    28 Oct 2026, 02:02 UTC

    The same notice was added 7 times, first on 21 Oct 2026, 17:05 UTC. The status did not change between them.

    Study results updated

  2. Versions 3 to 5

    21 Oct 2026, 16:35 UTC

    The same notice was added 3 times, first on 21 Oct 2026, 16:35 UTC. The status did not change between them.

    Study data updated · source update from Europe PMC

  3. Version 2

    9 Oct 2026, 18:17 UTC

    Study results updated

  4. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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