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Study · Animal study (in vivo) · rat · 2001

3 results

Comparative study of modulatory effects of Semax and primary proline-containing peptides on hemostatic reactions.

Cherkasova KA, Lyapina LA, Ashmarin IP

Bulletin of experimental biology and medicine1 Jul 2001Cited by 3 (Europe PMC)

PMID11687836 (opens in a new tab)DOI10.1023/a:1012503606536 (opens in a new tab)PepBankPUB-11687836
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats, intranasal Semax for 5 days enhanced the anticoagulant and fibrinolytic potential of the plasma.

    In plain wordsIn rats, Semax given through the nose for 5 days increased the blood's ability to prevent and break down clots.

    Peptide
    Semax
    Outcome
    IncreasePlasma fibrinolytic and anticoagulant potential
    Study

    ratn: not reported in source

    Outcome group
    Bleeding and clotting · Cardiovascular
    Studied dose
    Dose not stated · intranasal · 5 daysAs given in this study (rat).

    Source sentences

    Summary
    Intranasal administration of Semax, peptide Pro-Gly-Pro, and a mixture of peptides Pro-Gly+Gly-Pro to rats for 5 days enhanced anticoagulant and fibrinolytic potential of the plasma (total fibrinolytic activity and plasmin and plasminogen activator activities) and decreased antiplasmin concentration.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats, intranasal Semax for 5 days decreased the plasma antiplasmin concentration.

    In plain wordsIn rats, Semax given through the nose for 5 days lowered antiplasmin, a blood protein that limits clot breakdown.

    Peptide
    Semax
    Outcome
    DecreasePlasma antiplasmin concentration
    Study

    ratn: not reported in source

    Outcome group
    Bleeding and clotting · Cardiovascular
    Studied dose
    Dose not stated · intranasal · 5 daysAs given in this study (rat).

    Source sentences

    Summary
    Intranasal administration of Semax, peptide Pro-Gly-Pro, and a mixture of peptides Pro-Gly+Gly-Pro to rats for 5 days enhanced anticoagulant and fibrinolytic potential of the plasma (total fibrinolytic activity and plasmin and plasminogen activator activities) and decreased antiplasmin concentration.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In rats with experimental thrombosis, Semax decreased the weight of thrombi.

    In plain wordsIn rats with experimental clots, Semax reduced the weight of the clots.

    Peptide
    Semax
    Outcome
    DecreaseThrombus weight in experimental thrombosis
    Study

    ratn: not reported in source

    Outcome group
    Bleeding and clotting · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Semax and Pro-Gly-Pro decreased the weight of thrombi during experimental thrombosis.
    1 context sentence
    Summary · context
    Intranasal administration of Semax, peptide Pro-Gly-Pro, and a mixture of peptides Pro-Gly+Gly-Pro to rats for 5 days

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 19:08 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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