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Study · In vitro (cells) · 2002

2 results

The enhancement of avian NK cell cytotoxicity by thymulin is not mediated by the regulation of IFN-gamma production.

Merlino PG, Marsh JA

Developmental and comparative immunology1 Jan 2002Cited by 5 (Europe PMC)

PMID11687268 (opens in a new tab)DOI10.1016/s0145-305x(01)00042-8 (opens in a new tab)PepBankPUB-11687268
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In avian splenocytes, overnight thymulin did not change the proportion of intracellular IFN-gamma-positive cells versus media control.

    In plain wordsIn bird cells, overnight thymulin did not change the proportion of IFN-gamma-positive cells compared with media control.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changeIntracellular IFN-gamma-positive cells
    Study

    n: not reported in source

    avian splenocytes
    Comparator
    media control
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated · overnightAs given in this study.

    Source sentences

    Summary
    a similar incubation with thymulin produced no change in the percentages of cells labeling positive for intracellular IFN-gamma when compared to the media control cells.
  2. 02LabIn vitro (cells)Mechanism

    In avian splenocytes, overnight thymulin did not induce IFN-gamma secretion.

    In plain wordsIn bird cells, overnight thymulin did not induce IFN-gamma secretion.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changeIFN-gamma secretion
    Study

    n: not reported in source

    avian splenocytes
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated · overnightAs given in this study.

    Source sentences

    Summary
    In addition, IFN-gamma was not secreted by splenocytes following an overnight incubation with thymulin, but increased secretion was induced by Con A stimulation.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 2

    21 Oct 2026, 13:55 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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