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Study · Animal study (in vivo) · rabbit · 2001

2 results

[Hypnogenic properties of DSIP peptide analogs: structural-functional relationship].

Koval'zon VM

Izvestiia Akademii nauk. Seriia biologicheskaia1 Jul 2001

PMID11525128 (opens in a new tab)PepBankPUB-11525128
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rabbits, DSIP injected into the lateral ventricle had no statistically significant effect on sleep compared with saline.

    In plain wordsIn rabbits, DSIP injected into the brain had no significant effect on sleep compared with saline.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeSleep-wake states
    Study

    rabbitn: not reported in source

    Comparator
    Saline control in the same animals
    Outcome group
    Sleep · Sleep
    Studied dose
    Dose not stated · injection into the lateral ventricle of the cerebrumAs given in this study (rabbit).

    Source sentences

    Summary
    DSIP and most analogs had no statistically significant effect on sleep compared to the control administration of saline to the same animals
    2 context sentences
    Summary · context
    The sleep-inducing activity of Delta Sleep-Inducing Peptide (DSIP) and its 13 synthetic analogs has been studied on rabbits with preliminary implanted electrodes.
    Summary · context
    The peptides were injected into the lateral ventricle of cerebrum.
  2. 02AnimalAnimal study (in vivo)Safety outcome

    In rabbits, DSIP injected into the lateral ventricle slightly increased body temperature.

    In plain wordsIn rabbits, DSIP injected into the brain slightly raised body temperature.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseBody temperature
    Study

    rabbitn: not reported in source

    Comparator
    Saline control in the same animals
    Outcome group
    Adverse events · Whole body
    Studied dose
    Dose not stated · injection into the lateral ventricle of the cerebrumAs given in this study (rabbit).

    Source sentences

    Summary
    In addition, this analog, as well as parent DSIP and four proline-containing nonapeptides, slightly increased the body temperature.
    2 context sentences
    Summary · context
    The sleep-inducing activity of Delta Sleep-Inducing Peptide (DSIP) and its 13 synthetic analogs has been studied on rabbits with preliminary implanted electrodes.
    Summary · context
    The peptides were injected into the lateral ventricle of cerebrum.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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