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Study · In vitro (cells) · turkey · 2001

4 results

The effect of insulin-like growth factor analogs on turkey satellite cell and embryonic myoblast proliferation.

Pesall JE, McFarland DC, McMurtry JP, Clapper JA, Francis GL, Gilkerson KK

Poultry science1 Jul 2001Cited by 5 (Europe PMC)

PMID11469659 (opens in a new tab)DOI10.1093/ps/80.7.944 (opens in a new tab)PepBankPUB-11469659
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Efficacy outcome

    In turkey satellite cells, chicken LR3 IGF-I was significantly less active than chicken IGF-I for proliferation.

    In plain wordsIn turkey muscle stem cells in a dish, an IGF-I analogue was less active than natural chicken IGF-I.

    Peptide
    IGF-1 LR3
    Outcome
    DecreaseSatellite cell proliferation
    Study

    turkeyn: not reported in source

    turkey satellite cells
    Comparator
    Chicken IGF-I
    Outcome group
    Muscle injury and repair · Musculoskeletal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    However, the chicken LR3 IGF-I analog was significantly less active toward satellite cells and embryonic myoblasts compared with chicken IGF-I.
    2 context sentences
    Summary · context
    The effects of several human and chicken insulin-like growth factor (IGF) analogs on turkey satellite cell and embryonic myoblast proliferation were examined in serum-free medium.
    Summary · context
    The biopotency of two analogs, which were modified to prevent interaction with IGF-binding proteins, was also examined.
  2. 02LabIn vitro (cells)Efficacy outcome

    In turkey embryonic myoblasts, chicken LR3 IGF-I was significantly less active than chicken IGF-I for proliferation.

    In plain wordsIn turkey embryonic muscle cells in a dish, an IGF-I analogue was less active than natural chicken IGF-I.

    Peptide
    IGF-1 LR3
    Outcome
    DecreaseEmbryonic myoblast proliferation
    Study

    turkeyn: not reported in source

    turkey embryonic myoblasts
    Comparator
    Chicken IGF-I
    Outcome group
    Muscle injury and repair · Musculoskeletal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    However, the chicken LR3 IGF-I analog was significantly less active toward satellite cells and embryonic myoblasts compared with chicken IGF-I.
    2 context sentences
    Summary · context
    The effects of several human and chicken insulin-like growth factor (IGF) analogs on turkey satellite cell and embryonic myoblast proliferation were examined in serum-free medium.
    Summary · context
    The biopotency of two analogs, which were modified to prevent interaction with IGF-binding proteins, was also examined.
  3. 03LabIn vitro (cells)Activity measurement

    In turkey satellite cells, chicken LR3 IGF-I had reduced ability to compete with labelled human IGF-I for receptor binding compared with chicken IGF-I.

    In plain wordsIn turkey muscle stem cells in a dish, an IGF-I analogue bound the IGF receptor less well than natural chicken IGF-I.

    Peptide
    IGF-1 LR3
    Outcome
    DecreaseIGF receptor binding in satellite cells
    Study

    turkeyn: not reported in source

    turkey satellite cells
    Comparator
    Chicken IGF-I
    Outcome group
    Receptor activity and mechanism · Musculoskeletal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Examination of IGF receptor binding characteristics revealed that chicken LR3 IGF-I had reduced ability to compete with [125I]hIGF-I for binding to satellite cells or embryonic myoblasts compared with chicken IGF-I.
    2 context sentences
    Summary · context
    The effects of several human and chicken insulin-like growth factor (IGF) analogs on turkey satellite cell and embryonic myoblast proliferation were examined in serum-free medium.
    Summary · context
    The biopotency of two analogs, which were modified to prevent interaction with IGF-binding proteins, was also examined.
  4. 04LabIn vitro (cells)Activity measurement

    In turkey embryonic myoblasts, chicken LR3 IGF-I had reduced ability to compete with labelled human IGF-I for receptor binding compared with chicken IGF-I.

    In plain wordsIn turkey embryonic muscle cells in a dish, an IGF-I analogue bound the IGF receptor less well than natural chicken IGF-I.

    Peptide
    IGF-1 LR3
    Outcome
    DecreaseIGF receptor binding in embryonic myoblasts
    Study

    turkeyn: not reported in source

    turkey embryonic myoblasts
    Comparator
    Chicken IGF-I
    Outcome group
    Receptor activity and mechanism · Musculoskeletal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Examination of IGF receptor binding characteristics revealed that chicken LR3 IGF-I had reduced ability to compete with [125I]hIGF-I for binding to satellite cells or embryonic myoblasts compared with chicken IGF-I.
    2 context sentences
    Summary · context
    The effects of several human and chicken insulin-like growth factor (IGF) analogs on turkey satellite cell and embryonic myoblast proliferation were examined in serum-free medium.
    Summary · context
    The biopotency of two analogs, which were modified to prevent interaction with IGF-binding proteins, was also examined.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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