Skip to content

Study · Animal study (in vivo) · rat · 2000

2 results

Effect of tetrapeptide cortagen on regeneration of sciatic nerve.

Turchaninova LN, Kolosova LI, Malinin VV, Moiseeva AB, Nozdrachev AD, Khavinson VK

Bulletin of experimental biology and medicine1 Dec 2000Cited by 3 (Europe PMC)

PMID11276314 (opens in a new tab)DOI10.1023/a:1017532001908 (opens in a new tab)PepBankPUB-11276314
Publisher pagePubMedAsk about this study
Jump to 2 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats after sciatic nerve transection and suturing, cortagen increased regenerating nerve fiber growth rate by 27%.

    In plain wordsIn rats after sciatic nerve injury and repair, cortagen increased regenerating nerve fiber growth rate by 27%.

    Peptide
    Cortagen (AEDP)
    Outcome
    IncreaseRegenerating nerve fiber growth rate
    Study

    ratn: not reported in source

    Sciatic nerve transection and suturing
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    10 microg/kg · intramuscular · 10 daysAs given in this study (rat).

    Measurements

    Growth rate increase
    27%
    regenerating nerve fibers

    Source sentences

    Summary
    Intramuscular injection of 10 microg/kg cortagen to rats during 10 days after transsection and suturing of the sciatic nerve increased the growth rate and conduction velocity in the regenerating nerve fibers by 27% and 40%, respectively.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats after sciatic nerve transection and suturing, cortagen increased regenerating nerve fiber conduction velocity by 40%.

    In plain wordsIn rats after sciatic nerve injury and repair, cortagen increased regenerating nerve fiber conduction velocity by 40%.

    Peptide
    Cortagen (AEDP)
    Outcome
    IncreaseRegenerating nerve fiber conduction velocity
    Study

    ratn: not reported in source

    Sciatic nerve transection and suturing
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    10 microg/kg · intramuscular · 10 daysAs given in this study (rat).

    Measurements

    Conduction velocity increase
    40%
    regenerating nerve fibers

    Source sentences

    Summary
    Intramuscular injection of 10 microg/kg cortagen to rats during 10 days after transsection and suturing of the sciatic nerve increased the growth rate and conduction velocity in the regenerating nerve fibers by 27% and 40%, respectively.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 17:05 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

PepBank is a research reference. Talk to a doctor before you use any peptide.